ReviewBiosensors2025
Rational Design of Covalent Organic Frameworks for Enhanced Reticular Electrochemiluminescence and Biosensing Applications.
Review in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Solid-state electrochemiluminescence sensor based on functional covalent organic frameworks for detecting CoMikrochimica acta · 2026Article
- Insights into Sensing and Biomedical Domains Using Multi-Synthetic Covalent Organic Frameworks.Biosensors · 2026Review
- Recent advances in functional materials for uranium monitoring through optical and electrochemical techniques.RSC advances · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electrochemiluminescence (ECL) has evolved into a powerful analytical technique due to its ultra-high sensitivity, low background noise, and precise electrochemical control. The development of efficient ECL emitters is central to advancing this technology for practical applications. Covalent organic frameworks (COFs) have recently emerged as promising candidates for constructing high-performance ECL systems. The tunable porosity, ordered π-conjugated structures, and versatile modular functionalities of COFs provide fast massive transport, effective electron transfer, rapid interfacial electrochemical reaction, and enhanced ECL emission performance. This review provides a comprehensive overview of the rational design strategies and structural engineering for COF-based ECL materials at the molecular level. Linkage chemistry, monomer selection (luminophores and π-conjugated non-ECL motifs), precise framework regulation, post-synthetic modification, composite formation, and other ECL enhancement strategies were discussed for developing COF-based ECL emitter. Both the incorporation of aggregation-induced emission and intramolecular charge transfer mechanisms are included to enhance ECL efficiency. Donor-acceptor conjugation, heteroatom element content, isomerism, substitution, and dimensional direction were regarded as effective strategies to regulate the electronic structure and band diagrams for designing high-performance ECL systems. The role of COFs as both active emitters and functional scaffolds for signal amplification is critically examined. Furthermore, their diverse analytical applications across biosensing, food safety, environmental monitoring, and chiral recognition are highlighted. By correlating structural features with ECL performance, this review offers insights into the design principles of next-generation reticular ECL materials and outlines future directions for their practical deployment in sensitive and selective sensing platforms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.