Evidence map›Paper›PMID 41294758›Full record

ArticleBiosensors2025

Construction of an Immunosensor Based on the Affinity DNA Functional Ligands to the Fc Segment of IgG Antibody.

Qianyu Yang, Zhiwei Liu, Xinrui Xu, Zihao Zhao, Ze Fan, Bin Du, Jianjie Xu, Jiwei Xu, Jiang Wang, Bing Liu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Qianyu YangState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Zhiwei LiuState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Xinrui XuState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Zihao ZhaoState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.ORCID 0009-0000-8808-8235
Ze FanState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Bin DuState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Jianjie XuState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Jiwei XuState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.ORCID 0000-0002-2423-8123
Jiang WangState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Bing LiuState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Xihui MuState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Zhaoyang TongState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.

Funding

State Key Laboratory of Chemistry for NBC Hazards Protection FHPB2023-3
6 · The paper itself

Abstract

Over the past few decades, Fc fragment-conjugated proteins, such as Protein A, have been extensively utilized across a range of applications, including antibody purification, site-specific immobilization of antibodies, and the development of biosensing platforms. In this study, building upon our group prior research, we designed and screened an affinity DNA functional ligand (A-DNAFL) and experimentally validated its binding affinity (

Indexed as

Biosensing TechniquesDNAImmunoglobulin Fc FragmentsImmunoglobulin GAnimalsImmunoassayLigandsMiceMolecular Docking SimulationDNAImmunoglobulin Fc FragmentsImmunoglobulin GLigandsdirectional immobilizationDNA functional ligandFc fragmentimmunosensortoxin detection

Identifiers

PMID41294758
PMCPMC12649849

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.