Evidence map›Paper›PMID 41294650›Full record

ReviewCurrent oncology (Toronto, Ont.)2025

Artificial Intelligence in Clinical Oncology: From Productivity Enhancement to Creative Discovery.

Masahiro Kuno, Hiroki Osumi, Shohei Udagawa, Kaoru Yoshikawa, Akira Ooki, Eiji Shinozaki, Tetsuo Ishikawa, Junna Oba, Kensei Yamaguchi, Kazuhiro Sakurada

Abstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Masahiro KunoDepartment of Gastroenterological Chemotherapy, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Hiroki OsumiDepartment of Gastroenterological Chemotherapy, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.ORCID 0000-0002-4742-0446
Shohei UdagawaDepartment of Gastroenterological Chemotherapy, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Kaoru YoshikawaDepartment of Gastroenterological Chemotherapy, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Akira OokiDepartment of Gastroenterological Chemotherapy, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Eiji ShinozakiDepartment of Gastroenterological Chemotherapy, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Tetsuo IshikawaThe Ishii-Ishibashi Laboratory, Department of Extended Intelligence for Medicine, Graduate School of Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan.ORCID 0000-0001-5418-5387
Junna ObaThe Ishii-Ishibashi Laboratory, Department of Extended Intelligence for Medicine, Graduate School of Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan.ORCID 0000-0002-2899-3919
Kensei YamaguchiDepartment of Gastroenterological Chemotherapy, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Kazuhiro SakuradaThe Ishii-Ishibashi Laboratory, Department of Extended Intelligence for Medicine, Graduate School of Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern clinical oncology faces an unprecedented data complexity that exceeds human analytical capacity, making artificial intelligence (AI) integration essential rather than optional. This review examines the dual impact of AI on productivity enhancement and creative discovery in cancer care. We trace the evolution from traditional machine learning to deep learning and transformer-based foundation models, analyzing their clinical applications. AI enhances productivity by automating diagnostic tasks, streamlining documentation, and accelerating research workflows across imaging modalities and clinical data processing. More importantly, AI enables creative discovery by integrating multimodal data to identify computational biomarkers, performing unsupervised phenotyping to reveal hidden patient subgroups, and accelerating drug development. Finally, we introduce the FUTURE-AI framework, outlining the essential requirements for translating AI models into clinical practice. This ensures the responsible deployment of AI, which augments rather than replaces clinical judgment, while maintaining patient-centered care.

Indexed as

Artificial IntelligenceMedical OncologyNeoplasmsHumansartificial intelligenceclinical oncologydeep learningfoundation modelsFUTURE-AI frameworklarge language modelmachine learningprecision medicineretrieval-augmented generation

Identifiers

PMID41294650
PMCPMC12651923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.