Evidence map›Paper›PMID 41294607›Full record

ArticleGels (Basel, Switzerland)2025

β-Cyclodextrin Inclusion Complexes of Curcumin and Synthetic Analogues in PVA/Carrageenan Hydrogels: A Platform for Sustained Release and Microbial Control.

Patricia Daiane Zank, Matheus da Silva Gularte, André Ricardo Fajardo, Matheus Pereira de Albuquerque, Vithor Parada Garcia, Rafaely Piccioni Rosado, Letícia Zibetti, Clarissa Piccinin Frizzo, Bruno Nunes da Rosa, Cláudio Martin Pereira de Pereira and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Patricia Daiane ZankBiology Research Laboratory, (LAPEBBIOM), Department of Chemical, Pharmaceutical, and Food Sciences, Microorganism Biochemistry and Molecular, Federal University of Pelotas, Pelotas 96010-610, RS, Brazil.
Matheus da Silva GularteLaboratory of Technology and Development of Composites and Polymeric Materials (LaCoPol), Federal University of Pelotas, Pelotas 96010-900, RS, Brazil.
André Ricardo FajardoLaboratory of Technology and Development of Composites and Polymeric Materials (LaCoPol), Federal University of Pelotas, Pelotas 96010-900, RS, Brazil.ORCID 0000-0001-5362-6478
Matheus Pereira de AlbuquerqueBiology Research Laboratory, (LAPEBBIOM), Department of Chemical, Pharmaceutical, and Food Sciences, Microorganism Biochemistry and Molecular, Federal University of Pelotas, Pelotas 96010-610, RS, Brazil.ORCID 0009-0007-2175-2374
Vithor Parada GarciaBiology Research Laboratory, (LAPEBBIOM), Department of Chemical, Pharmaceutical, and Food Sciences, Microorganism Biochemistry and Molecular, Federal University of Pelotas, Pelotas 96010-610, RS, Brazil.
Rafaely Piccioni RosadoBiology Research Laboratory, (LAPEBBIOM), Department of Chemical, Pharmaceutical, and Food Sciences, Microorganism Biochemistry and Molecular, Federal University of Pelotas, Pelotas 96010-610, RS, Brazil.
Letícia ZibettiHeterocycle Chemistry Nucleus (NUQUIMHE), Federal University of Santa Maria, Santa Maria 97105-340, RS, Brazil.
Clarissa Piccinin FrizzoHeterocycle Chemistry Nucleus (NUQUIMHE), Federal University of Santa Maria, Santa Maria 97105-340, RS, Brazil.ORCID 0000-0002-1175-7880
Bruno Nunes da RosaLipidomics and Bioorganic Laboratory, Center for Chemical, Pharmaceutical and Food Sciences, Federal University of Pelotas, Pelotas 96010-900, RS, Brazil.
Cláudio Martin Pereira de PereiraLipidomics and Bioorganic Laboratory, Center for Chemical, Pharmaceutical and Food Sciences, Federal University of Pelotas, Pelotas 96010-900, RS, Brazil.
Janice Luehring GiongoFaculty of Medicine (FAMED), Pharmacy of Course, Federal University of Rio Grande, Rio Grande 92203-900, RS, Brazil.
Rodrigo de Almeida VaucherBiology Research Laboratory, (LAPEBBIOM), Department of Chemical, Pharmaceutical, and Food Sciences, Microorganism Biochemistry and Molecular, Federal University of Pelotas, Pelotas 96010-610, RS, Brazil.ORCID 0000-0002-8306-9243

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study describes the development of β-cyclodextrin (β-CD) inclusion complexes of curcumin (CUR) and a synthetic curcuminoid analogue (CN56), which were incorporated into poly(vinyl alcohol)/κ-carrageenan hydrogel films to create a multifunctional system capable of sustained drug release and effective antimicrobial action. Carrageenan was extracted from

Indexed as

antimicrobial activitydrug delivery systemsGardnerella vaginalisvaginal infectionswomen’s health

Identifiers

PMID41294607
PMCPMC12652160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.