Evidence map›Paper›PMID 41294309›Full record

ReviewDevelopment (Cambridge, England)2024

Primate amnion development.

Nikola Sekulovski, Amber E Carleton, Chien-Wei Lin, Kenichiro Taniguchi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Development (Cambridge, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nikola SekulovskiDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Amber E CarletonDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Chien-Wei LinDivision of Biostatistics, Data Science Institute, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Kenichiro TaniguchiDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

Funding

Molecular regulators of human amniogenesisR01HD098231 · NICHD · MEDICAL COLLEGE OF WISCONSIN · PI Kenichiro Taniguchi · 2019 to 2026
$3.3M
National Institute of Child Health and Human Development R01-HD098231NICHD NIH HHS R01 HD098231
6 · The paper itself

Abstract

Formation of the amnion in humans is crucial for fetal development and a healthy pregnancy. In addition to providing a protective layer to the developing fetus as a component of the amniochorionic fetal membranes, the amnion serves as a signaling center for patterning early embryonic tissues. However, because the amnion is first specified in the human epiblast during implantation, the molecular and cellular events of this early amniogenic process in humans cannot be studied in utero. Recent developments using new human stem cell-derived model systems, as well as single-cell and spatial transcriptomic analyses of early human and monkey embryos, have uncovered new insights into the underpinnings of primate amnion specification. Here, we highlight recent findings from human and monkey models with an emphasis on current understandings of morphogenesis, BMP-driven transcriptional signatures and key players associated with primate amniotic ectoderm specification.

Indexed as

AmnionPrimatesAnimalsBone Morphogenetic ProteinsFemaleGene Expression Regulation, DevelopmentalHumansMorphogenesisPregnancySignal TransductionBone Morphogenetic ProteinsAmnionEarly human developmentHuman pluripotent stem cells

Identifiers

PMID41294309
PMCPMC12701618

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.