ArticleHuman brain mapping2025
Discordance Between Spatial and Population Correlations From Human Brain Imaging Data.
Article in Human brain mapping, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Discordance Between Spatial and Population Correlations From Human Brain Imaging Data.Human brain mapping · 2025Article
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Authors and funding
5 authors.
Funding
Abstract
It has become increasingly common to probe correlations between human brain imaging measures of receptor/protein binding and function using population-level brain maps, typically drawn from independent cohorts to estimate correlations across regions. This strategy raises issues of interpretation that we highlight here with both an empirical multimodal brain imaging dataset and simulation studies. Twenty-four healthy participants completed neuroimaging with both [11C]Cimbi-36 positron emission tomography and magnetic resonance imaging scans to estimate receptor binding potential (BP) and cerebral blood flow (CBF), respectively, in 18 cortical/subcortical regions. Correlations between BP and CBF were estimated in four ways: (1) Pearson correlation across regions of mean regional BP and CBF from a single or separate cohorts (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.