Evidence map›Paper›PMID 41294224›Full record

Observational studyEpidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil2025

Hospitalizations due to stroke and their relationship with Chagas disease: a population-based analytical study using data from the Hospital Information System of the Brazilian National Health System, Minas Gerais, Brazil, 2022.

Ana Clara de Jesus Santos, Nayara Dornela Quintino, Jeniffer Eduarda Firmino Almeida Silva, Maria do Carmo Pereira Nunes, João Alves Pereira, Ester Cerdeira Sabino, Ariela Ferreira Mota, Desirée Sant'Ana Haikal

Erratum issuedAbstract readObservational Study
In one paragraph

Observational study in Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Ana Clara de Jesus SantosUniversidade Estadual de Montes Claros, Programa de Pós-Graduação em Ciências da Saúde, Montes Claros, MG, Brazil.ORCID http://orcid.org/0000-0003-1821-2338
Nayara Dornela QuintinoSecretaria de Estado de Saúde de Minas Gerais, Unidade Regional de Saúde de Divinópolis, Divinópolis, MG, Brazil.ORCID http://orcid.org/0000-0001-5740-0310
Jeniffer Eduarda Firmino Almeida SilvaUniversidade Estadual de Montes Claros, Departamento de Enfermagem, Montes Claros, MG, Brazil.ORCID http://orcid.org/0009-0001-7234-0819
Maria do Carmo Pereira NunesUniversidade Federal de Minas Gerais, Departamento de Medicina Interna, Belo Horizonte, MG, Brazil.ORCID http://orcid.org/0000-0001-8505-3432
João Alves PereiraSecretaria de Estado de Saúde de Minas Gerais, Montes Claros, MG, Brazil.ORCID http://orcid.org/0000-0003-0980-4454
Ester Cerdeira SabinoUniversidade de São Paulo, Faculdade de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-2623-5126
Ariela Ferreira MotaUniversidade Estadual de Montes Claros, Programa de Pós-Graduação em Ciências da Saúde, Montes Claros, MG, Brazil.ORCID http://orcid.org/0000-0002-2315-5318
Desirée Sant'Ana HaikalUniversidade Estadual de Montes Claros, Programa de Pós-Graduação em Ciências da Saúde, Montes Claros, MG, Brazil.ORCID http://orcid.org/0000-0002-0331-0747

Funding

"Sao Paulo-Minas Gerais Center for Chagas Disease Treatment (SaMiTrop)"U01AI168383 · NIAID · FUNDACAO FACULDADE DE MEDICINA · PI Ester Cerdeira Sabino · 2022 to 2026
$1.9M
NIAID NIH HHS U01 AI168383
6 · The paper itself

Abstract

objectiveTo assess whether hospitalizations due to stroke were associated with Chagas disease and the Chagas disease vulnerability index in the state of Minas Gerais.

methodsThis was a population-based analytical observational study. Data were obtained from the Hospital Information System of the Brazilian National Health System in Minas Gerais for the year 2022. Hospitalization records were selected based on the International Statistical Classification of Diseases and Related Health Problems, in which stroke was recorded as the primary cause and Chagas disease/sentinels as the secondary cause. Stroke-related hospitalization rates were estimated, and a correlation analysis was conducted between the Chagas disease vulnerability index and stroke hospitalization prevalence in Minas Gerais and its health macro-regions.

resultsIn 2022, a total of 25,813 hospitalizations due to stroke as the primary cause were recorded, of which only 18 included Chagas disease/sentinels as the secondary cause, most of them in the Central macro-region (n=10). The correlation between stroke-related hospitalizations and the Chagas disease vulnerability index was weak (r=0.145) and not statistically significant, despite the overlap of macro-regions with higher stroke-related hospitalization rates and higher Chagas disease vulnerability index scores (Jequitinhonha Valley and North).

conclusionAlthough there was a high number of stroke-related hospitalizations in the Brazilian National Health System in Minas Gerais, only 18 of these records were associated with Chagas disease/sentinels, which may suggest underreporting of Chagas disease and uncertainty regarding the quality of such records.

Indexed as

Chagas DiseaseHospitalizationStrokeAdolescentAdultAgedBrazilFemaleHospital Information SystemsHumansMaleMiddle AgedNational Health ProgramsPrevalenceYoung Adult

Identifiers

PMID41294224
PMCPMC12641598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.