ArticleBrazilian dental journal2025
How the NaOCl solution concentration and temperature impact chlorine levels, tissue dissolution and pH.
Article in Brazilian dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Influence of Passive Ultrasonic Irrigation (PUI) on the Healing of Maxillary Sinusitis of Endodontic Origin (MSEO) After Non-Surgical Endodontic Treatment.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study analyzed the behavior of sodium hypochlorite (NaOCl) at various concentrations and temperatures in relation to free available chlorine (FAC), tissue dissolution (TD), and pH. NaOCl solutions (2.50%, 5.25%, and 8.00% w/v) and distilled water (H2O) were evaluated. Each solution was heated to different temperatures (25°C, 37°C, and 60°C) for periods of 5 minutes, 10 minutes, and 15 minutes. For tissue dissolution analysis, bovine tissue samples (n = 10) were immersed in each solution and weighed before and after the designated times. FAC and pH were measured after each heating time. Data normality and homoscedasticity were verified using the Shapiro-Wilk and Levene tests. Solubility data were analyzed using the Kruskal-Wallis test and the Dwass-Steel-Critchlow-Fligner post-hoc test, and pH data were analyzed using one-way ANOVA and the Tukey post-hoc test. FAC data were subjected to a Student's t-test (α = 0.05%). At 25°C, all NaOCl concentrations had similar dissolution effects (p>0.05) and were superior to H2O (p<0.05). At 37°C, the dissolution effect of 2.5% NaOCl was similar to water after 5 min (p>0.05). NaOCl at 5.25% and 8.00% dissolved 90-100% of the samples after 10-15 min (37°C and 60°C). FAC in 2.50% NaOCl decreased when heated (37°C and 60°C), and 5.25% NaOCl showed a FAC reduction at 60°C (p<0.05). NaOCl at 8.00% showed similar results at all temperatures (p>0.05). The pH decreased (p<0.05) at 37°C and 60°C. Increasing NaOCl concentration, temperature, and heating time enhanced the tissue dissolution effect. Higher temperatures also reduced the FAC concentration in 2.50% and 5.25% NaOCl, as well as the pH in all evaluated NaOCl concentrations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.