Observational studySao Paulo medical journal = Revista paulista de medicina2025
Impact of thyroid volume on serum ionized calcium and PTH levels after total thyroidectomy.
Observational study in Sao Paulo medical journal = Revista paulista de medicina, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
backgroundThe relationship between thyroid gland volume and hypoparathyroidism after total thyroidectomy remains controversial.
objectiveTo evaluate thyroid gland mass as a risk factor for hypoparathyroidism after total thyroidectomy. DESIGN AND
settingA Retrospective cross-sectional observational study was conducted at Centro Universitário Lusíada (UNILUS), Santos/SP, Brazil.
methodsPatients undergoing total thyroidectomy between January 2022 and September 2023 were retrospectively evaluated for serum levels of ionized calcium and ultrasensitive parathyroid hormone (PTH), measured preoperatively and 30-60 days postoperatively, and thyroid mass, obtained by weighing the specimen.
resultsA total of 174 patients were evaluated, with a predominance of women (89.7%), a median age of 50.5 years, and a median goiter volume of 36.3 mL. A reduction in both PTH and ionized calcium levels was observed in the postoperative period compared with the preoperative period (P < 0.05). No significant changes were observed in PTH levels and volume (P = 0.481). For calcium, there was a tendency towards an association between volume measurements and its change between the pre- and postoperative periods, which was marginally significant (P = 0.051).
conclusionThere was a marginal association between volume and changes in pre- and postoperative ionized calcium levels, but no significant association with pre- and postoperative PTH measurements.
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