Evidence map›Paper›PMID 41294081›Full record

ArticleSuicide & life-threatening behavior2025

Prescription Opioid Misuse and the Perceived Likelihood of Future Suicidal Behavior: Considering the Role of Suicide Capability Dimensions.

Zachary T DeMoss, Matthew T Tull, Kim L Gratz

Abstract read
In one paragraph

Article in Suicide & life-threatening behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zachary T DeMossDepartment of Psychology, University of Toledo, Toledo, Ohio, USA.
Matthew T TullDepartment of Psychology, University of Toledo, Toledo, Ohio, USA.ORCID https://orcid.org/0000-0002-1382-117X
Kim L GratzDepartment of Psychology, University of Toledo, Toledo, Ohio, USA.ORCID https://orcid.org/0000-0002-2659-6784

Funding

University of Toledo
6 · The paper itself

Abstract

introductionIn the past two decades, suicide attempts and deaths involving prescription opioids have sharply increased. Research is needed to understand how prescription opioid misuse may increase suicide risk. Contemporary suicide theories suggest opioid use may increase suicide capability by increasing pain tolerance, altering fears related to death, or increasing one's understanding of lethal doses and/or access to means. This study examined the role of these dimensions of suicide capability in the association between prescription opioid misuse and self-reported likelihood of future suicidal behaviors.

methodsIndividuals with chronic pain, past year depression, and a current prescription of opioids for pain (N = 166) completed assessments of opioid misuse, suicide capability (i.e., fearlessness about death, pain tolerance, and suicide preparation and rehearsal), and suicidal behaviors.

resultsAnalyses demonstrated significant indirect relations of prescription opioid misuse to the perceived future likelihood of suicide planning and attempts (both in general and involving opioids specifically) through suicide capability in the form of suicide preparation and rehearsal, controlling for suicide attempt history.

conclusionFindings suggest that prescription opioid misuse may increase suicide risk by increasing familiarity with a potential suicide method, consistent with extant literature highlighting the role of practical suicide capability in suicide risk.

Indexed as

Analgesics, OpioidOpioid-Related DisordersPrescription Drug MisuseSuicidal IdeationSuicideSuicide, AttemptedAdultChronic PainFemaleHumansMaleMiddle AgedYoung AdultAnalgesics, Opioidchronic painopioid misusepractical suicide capabilitysuicide capabilitysuicide risk

Identifiers

PMID41294081
PMCPMC12649308

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.