Evidence map›Paper›PMID 41294001›Full record

ReviewWomen's health (London, England)

Disparities in women's health and clinical considerations from a translational science perspective: A narrative review and framework for future directions.

Alison Warren, Krista Garrett, Leigh A Frame

Abstract readReview
In one paragraph

Review in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alison WarrenDepartment of Clinical Research and Leadership, School of Medicine and Health Sciences, George Washington University, DC, USA.ORCID 0000-0001-9290-3319
Krista GarrettCoastal Carolina University, Conway, SC, USA.
Leigh A FrameDepartment of Clinical Research and Leadership, School of Medicine and Health Sciences, George Washington University, DC, USA.ORCID 0000-0002-1475-2778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSex and gender disparities persist across biomedical research, clinical care, and health policy, despite increasing recognition of sex-specific disease mechanisms and treatment responses. Underrepresentation of women in clinical trials continues to produce male-centric treatment protocols and insufficient data to support precision care.

methodsThis narrative review applies a translational science framework to examine recurring and cross-cutting gaps in sex and gender health science. Rather than cataloging all disease areas, the review uses three exemplar domains-mental and neurological conditions, autoimmune disorders, and cardiovascular disease-to illustrate patterns observed across the research-to-policy continuum.

resultsFindings reveal persistent issues including underrepresentation of women in research, inadequate sex-disaggregated data, and structural biases that impede equitable evidence development. These challenges appear consistently across basic science, clinical research, guideline development, and health policy translation.

conclusionsTo advance equitable, evidence-based care, recommendations include adopting intersectional frameworks, improving sex-disaggregated data practices, increasing investment in sex-based research, and integrating sex and gender health science into medical education. Addressing these gaps through a translational lens is essential to achieving precision medicine that effectively serves all individuals.

Indexed as

Healthcare DisparitiesHealth Status DisparitiesTranslational Science, BiomedicalWomen's HealthCardiovascular DiseasesFemaleHealth PolicyHumansTranslational Research, Biomedicalgenderknowledge translationpublic healthtranslational sciencewomen’s health

Identifiers

PMID41294001
PMCPMC12657800

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.