Evidence map›Paper›PMID 41293996›Full record

ArticleBioFactors (Oxford, England)

ASNS Regulates H

Xiangyang Xin, Xin Zhao, Xiaobo Han, Wenhan Pu

Abstract read
In one paragraph

Article in BioFactors (Oxford, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. ASNS Regulates HBioFactors (Oxford, England)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiangyang XinDepartment of Ophthalmology, Baotou Central Hospital, Baotou, China.ORCID https://orcid.org/0000-0002-0619-5318
Xin ZhaoDepartment of Ophthalmology, Baogang Hospital of Inner Mongolia, Baotou, China.
Xiaobo HanDepartment of Ophthalmology, Baogang Hospital of Inner Mongolia, Baotou, China.
Wenhan PuDepartment of Ophthalmology, Baogang Hospital of Inner Mongolia, Baotou, China.

Funding

Science and Technology Program of the Joint Fund of Scientific Research for the Public Hospitals of InnerMongolia Academyof Medical Sciences 2023GLLH0239Scientific Research Program of Aerospace Medical and Healthcare Technology Group Co. 2023YK17
6 · The paper itself

Abstract

Age-related macular degeneration (AMD) is a common degenerative disease of the eye that ultimately leads to irreversible vision loss. Asparagine synthase (ASNS) is an aminotransferase, and its low expression is associated with retinal damage. The present study centered on the protective effect of ASNS on retinal epithelial cells. We found that in the AMD cell model, overexpression of ASNS reduced SA-β-gal staining and ROS production, and increased cell viability in H

Indexed as

GlucoseMacular DegenerationAnimalsCell LineCell SurvivalCellular SenescenceDisease Models, AnimalHumansHydrogen PeroxideOxidative StressReactive Oxygen SpeciesRetinal Pigment EpitheliumGlucoseHydrogen PeroxideReactive Oxygen Speciesage‐related macular degenerationARPE‐19 cellsASNSglycolysisUSP13

Identifiers

PMID41293996
PMCPMC12648640

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.