Evidence map›Paper›PMID 41293699›Full record

ArticleBiomedical optics express2025

Keratoconus diagnosis based on macro-micro corneal characteristics via optical coherence tomography.

Changyong Chen, Fan Zhang, Yun Tang, Huidou Cao, Lingmei Chen, Shuhao Qian, Lu Yang, Jia Meng, Rushan Jiang, Chuncheng Wang and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Changyong ChenState Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang 310027, China.ORCID https://orcid.org/0009-0003-3722-776X
Fan ZhangState Key Laboratory of Eye Health, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.
Yun TangState Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang 310027, China.
Huidou CaoState Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang 310027, China.
Lingmei ChenState Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang 310027, China.
Shuhao QianState Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang 310027, China.ORCID https://orcid.org/0000-0002-5276-2045
Lu YangState Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang 310027, China.
Jia MengState Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang 310027, China.
Rushan JiangState Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang 310027, China.
Chuncheng WangState Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang 310027, China.
Shuangmu ZhuoSchool of Science, Jimei University, Xiamen, Fujian 361021, China.
Zhihua DingState Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang 310027, China.ORCID https://orcid.org/0000-0003-2554-3741
Meixiao ShenState Key Laboratory of Eye Health, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.
Zhangliang LiState Key Laboratory of Eye Health, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.
Fangjun BaoState Key Laboratory of Eye Health, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.
Yun-E ZhaoState Key Laboratory of Eye Health, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.
Zhiyi LiuState Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang 310027, China.ORCID https://orcid.org/0000-0002-8122-8474

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Keratoconus is an ophthalmopathy characterized by a central thinning that commonly causes irregular astigmatism and high myopia. However, the diagnostic standards of keratoconus have not yet been well established clinically and mainly rely on macro characteristics measured through corneal topography. To describe the micro changes conveyed by collagen microstructures in the corneal stroma and provide a new insight for keratoconus, we developed a quantitative diagnostic method combining macro-micro information via

Identifiers

PMID41293699
PMCPMC12642995

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.