Evidence map›Paper›PMID 41293691›Full record

ArticleBiomedical optics express2025

Quantitative analysis of gingival vascular morphology using optical coherence tomography angiography in induced gingivitis.

Nhan Minh Le, Geng Wang, Zhiying Xie, Cheng Feng Yue, Shatha Bamashmous, Hrebesh Subhash, LaTonya Kilpatrick-Liverman, Diane M Daubert

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nhan Minh LeDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, USA.ORCID https://orcid.org/0000-0003-4555-5678
Geng WangDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, USA.ORCID https://orcid.org/0000-0002-5615-4696
Zhiying XieDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, USA.
Cheng Feng YueDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, USA.ORCID https://orcid.org/0000-0001-9851-0030
Shatha BamashmousDepartment of Periodontology, Faculty of Dentistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID https://orcid.org/0000-0003-1078-5991
Hrebesh SubhashColgate-Palmolive Company, Piscataway, New Jersey 08854, USA.ORCID https://orcid.org/0000-0003-3275-8847
LaTonya Kilpatrick-LivermanColgate-Palmolive Company, Piscataway, New Jersey 08854, USA.ORCID https://orcid.org/0009-0009-0383-8339
Diane M DaubertDepartment of Periodontics, University of Washington, Seattle, Washington 98195, USA.ORCID https://orcid.org/0000-0002-7307-4102

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated optical coherence tomography angiography (OCTA) for monitoring gingival vascular changes during induced inflammation and resolution. Twelve healthy participants abstained from brushing for 14 days, followed by 14 days of resumed oral hygiene. Vascular changes were quantified using vessel area density (VAD), vessel skeleton density (VSD), and vessel diameter index (VDI). VSD showed minimal change, whereas VAD increased by 13.6% and VDI by 10.1% at peak inflammation (P < 0.01). Participants were classified as high or low responders based on their gingival response. OCTA enabled site-specific, noninvasive assessment of gingival inflammation, detecting early microvascular alterations during disease progression.

Identifiers

PMID41293691
PMCPMC12643010

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.