Evidence map›Paper›PMID 41293684›Full record

ArticleBiomedical optics express2025

Highly transparent elastic optical microcavities for interferometric mapping of cell mechanics.

F Busse, J H Booth, N M Kronenberg, Y Sun, A T Meek, A Mischok, S R Pulver, M C Gather

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

F BusseHumboldt Centre for Nano- and Biophotonics, Department of Chemistry and Biochemistry, University of Cologne, Cologne, Germany.
J H BoothHumboldt Centre for Nano- and Biophotonics, Department of Chemistry and Biochemistry, University of Cologne, Cologne, Germany.
N M KronenbergHumboldt Centre for Nano- and Biophotonics, Department of Chemistry and Biochemistry, University of Cologne, Cologne, Germany.
Y SunHumboldt Centre for Nano- and Biophotonics, Department of Chemistry and Biochemistry, University of Cologne, Cologne, Germany.
A T MeekHumboldt Centre for Nano- and Biophotonics, Department of Chemistry and Biochemistry, University of Cologne, Cologne, Germany.
A MischokHumboldt Centre for Nano- and Biophotonics, Department of Chemistry and Biochemistry, University of Cologne, Cologne, Germany.
S R PulverCentre of Biophotonics, University of St Andrews, United Kingdom.
M C GatherHumboldt Centre for Nano- and Biophotonics, Department of Chemistry and Biochemistry, University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-4857-5562

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elastic resonator interference stress microscopy (ERISM) enables label-free, non-invasive measurements of cellular forces by detecting the cell-induced deformation of an optical microcavity using optical interference. Here, we present an improved microcavity design that utilizes a high-refractive-index elastomer, eliminating the need for the top metal layer required in traditional ERISM microcavities. This simplifies the fabrication process, offers improved control over mechanical properties, and enhances the resolution of ERISM measurements. The design is compatible with various bio-coatings, maintains long-term cell viability, and significantly improves optical transmission. This enables integrated and confocal fluorescence imaging with improved contrast over traditional ERISM microcavities.

Identifiers

PMID41293684
PMCPMC12643016

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.