Evidence map›Paper›PMID 41293610›Full record

ReviewCureus2025

Penile Traction Therapy for Peyronie's Disease: A Contemporary Narrative Review of Clinical Evidence and Evolving Trends.

Praveen Gopi, Muhammed Ishfaq, Shopon Kumer Das, Zakaria W Shkoukani, Altaf Q Khattak, Alaa Chamsin, Ninaad Awsare, Rachel Birley, Kaylie E Hughes

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Praveen GopiDepartment of Urology, Mersey and West Lancashire Teaching Hospitals NHS Trust, Prescot, GBR.
Muhammed IshfaqDepartment of Urology, Mersey and West Lancashire Teaching Hospitals NHS Trust, Prescot, GBR.
Shopon Kumer DasDepartment of Urology, Mersey and West Lancashire Teaching Hospitals NHS Trust, Prescot, GBR.
Zakaria W ShkoukaniDepartment of Urology, Mersey and West Lancashire Teaching Hospitals NHS Trust, Prescot, GBR.
Altaf Q KhattakDepartment of Urology, Mersey and West Lancashire Teaching Hospitals NHS Trust, Prescot, GBR.
Alaa ChamsinDepartment of Urology, Mersey and West Lancashire Teaching Hospitals NHS Trust, Prescot, GBR.
Ninaad AwsareDepartment of Urology, Mersey and West Lancashire Teaching Hospitals NHS Trust, Prescot, GBR.
Rachel BirleyDepartment of Urology, Mersey and West Lancashire Teaching Hospitals NHS Trust, Prescot, GBR.
Kaylie E HughesDepartment of Urology, Mersey and West Lancashire Teaching Hospitals NHS Trust, Prescot, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peyronie's disease (PD) is a connective tissue disorder of the penile tunica albuginea that leads to curvature, deformity, and erectile dysfunction, resulting in significant psychosocial distress. Surgical interventions remain effective but are often reserved for severe deformities. Over the past decade, penile traction therapy (PTT) has gained recognition as a non-invasive alternative based on the principle of mechanotransduction, offering the potential to remodel fibrotic tissue, reduce curvature, and restore length. A structured narrative review was performed using PubMed, ScienceDirect, and Wiley Online Library databases covering publications from 2009 to 2025. Search terms included 'Peyronie's disease', 'penile traction therapy', 'traction device', and 'RestoreX'. Eligible studies comprised randomised controlled trials (RCTs), prospective cohorts, meta-analyses, and systematic or narrative reviews investigating PTT as monotherapy or in combination with adjunctive treatments. Extracted data included sample size, device used, treatment protocol, outcomes such as curvature reduction, length gain, erectile function, satisfaction, and adverse events. A total of 15 major studies, including over 1,000 patients, were reviewed. Modern devices such as RestoreX and Penimaster PRO achieved mean curvature reductions of 20-30% and penile length gains averaging 1.5-2.3 cm with high adherence exceeding 85%. Short-duration protocols of 30-90 minutes daily showed similar or improved efficacy compared to older devices requiring prolonged wear. Adjunctive use of PTT with collagenase

Indexed as

curvature correctionerectile functionpenile traction therapypeyronie’s diseaserestorex device

Identifiers

PMID41293610
PMCPMC12641373

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.