ArticleTransboundary and emerging diseases2025
Serological Evidence of Highly Pathogenic Avian Influenza (H5N1) in Invasive Wild Pigs in Western Canada.
Article in Transboundary and emerging diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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9 authors.
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Abstract
Influenza A virus (IAV) can infect a wide range of hosts, including wild and domestic pigs. Swine play an important role in influenza evolution and epidemiology due to their ability to get infected with both avian and human influenza viruses, potentially leading to reassorted virus variants. Interactions at the wild-domestic swine interface have been documented on multiple occasions, raising concern about pathogen transmission and the emergence of novel influenza strains. This study investigates the occurrence and subtypes of IAV infecting invasive wild pigs in Alberta, Canada. A total of 267 wild pigs were captured between 2021-2024. Exposure to IAV was initially detected by cELISA, with further confirmation of exposure to the H5Nx virus by hemagglutination inhibition (HI) and virus neutralization (VN) assays. Although no IAV genetic material was detected by qPCR, the seropositive samples by cELISA (4.17%; 5/120) coincided with the 2022-2024 highly pathogenic avian influenza virus (HPAI) H5N1 epizootic in Alberta, which involved outbreaks in wild species and domestic birds. These findings, combined with the epidemiological context, suggest interspecies transmission of HPAI H5N1 clade 2.3.4.4b to wild pigs. These results highlight the potential role of wild pigs as a new host in Canada and emphasize the need for continued surveillance of IAV in wild pig populations to assess the risk of spillover events at the wildlife, livestock, and human interfaces.
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