Evidence map›Paper›PMID 41293410›Full record

ArticleFrontiers in neurology2025

Comparison of endovascular therapy care and outcome in primary and comprehensive stroke centers for acute ischemic stroke in China a real-world nationwide registry.

Ting-Yu Yi, Shujuan Gan, Meihua Wu, Weifeng Huang, Yanmin Wu, Hanming Tu, Changjun Yang, Lihua Xu, Hui Tan, Lin Gao and 23 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Ting-Yu YiCerebrovascular and Neuro-Intervention Department, Zhangzhou Affiliated Hospital of Fujian Medical University, Fujian, China.
Shujuan GanDepartment of Neurology, The Second Hospital of Zhangzhou, Fujian, China.
Meihua WuCerebrovascular and Neuro-Intervention Department, Zhangzhou Affiliated Hospital of Fujian Medical University, Fujian, China.
Weifeng HuangDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, China.
Yanmin WuCerebrovascular and Neuro-Intervention Department, Zhangzhou Affiliated Hospital of Fujian Medical University, Fujian, China.
Hanming TuDepartment of Neurology, Yongkang First People's Hospital, Zhejiang, China.
Changjun YangDepartment of Neurology, Sinan County People's Hospital of Guizhou province, Zhejiang, China.
Lihua XuDepartment of Neurology, Jiamusi Central Hospital, Heilongjiang, China.
Hui TanDepartment of Neurology, Taoyuan Country People's Hospital of Hunan province, Hunan, China.
Lin GaoDepartment of Neurology, Fukang General Hospital of Liaoning Health Industry Group, Liaoning, China.
Shuguang ZhaoDepartment of Neurology,Taihe County People's Hospital, Anhui, China.
Linping WeiDepartment of Neurology, Longchuan County People's Hospital, Guangdong, China.
Yingchun WuDepartment of Neurology,ORDOS central hospital, Neimenggu, China.
Guiguan YangDepartment of Neurology, Xingguo People's Hospital, Jiangxi, China.
Jian YeDepartment of Neurology, Fuqing Hospital Affiliated of Fujian Medical University, Fujian, China.
Dongsheng JuDepartment of Neurology, Songyuan Jilin Oilfield Hospital, Songyuan, Jilin, China.
Ya ShaoDepartment of Cerebrovascular Disease, Gansu Provincial Hospital of TCM, Gansu, China.
Zaihui ZhangDepartment of Neurology, Xiu Yan People's Hospital, Liaoning, China.
Junfeng SuDepartment of Neurology, Jingzhou Hospital Affiliated to Yangtze University, Hubei, China.
Shijun ZhaoDepartment of Interventional, Tangshanfengrun county People's Hospital, Shandong, China.
Weidong HuangDepartment of Neurology, Xinhui People's Hospital, Guangdong, China.
Xinshan WuDepartment of Neurology, Bayinggolin Mongolian Autonomous Prefecture People's Hospital, Xinjiang, China.
Dinglai LinCerebrovascular and Neuro-Intervention Department, Zhangzhou Affiliated Hospital of Fujian Medical University, Fujian, China.
Xiaohui LinCerebrovascular and Neuro-Intervention Department, Zhangzhou Affiliated Hospital of Fujian Medical University, Fujian, China.
ZhiNan PanCerebrovascular and Neuro-Intervention Department, Zhangzhou Affiliated Hospital of Fujian Medical University, Fujian, China.
Xiufen ZhengCerebrovascular and Neuro-Intervention Department, Zhangzhou Affiliated Hospital of Fujian Medical University, Fujian, China.
Ganji HongCerebrovascular and Neuro-Intervention Department, Zhangzhou Affiliated Hospital of Fujian Medical University, Fujian, China.
Rongcheng ChenCerebrovascular and Neuro-Intervention Department, Zhangzhou Affiliated Hospital of Fujian Medical University, Fujian, China.
Lisan ZengCerebrovascular and Neuro-Intervention Department, Zhangzhou Affiliated Hospital of Fujian Medical University, Fujian, China.
Thanh N NguyenDepartment of Neurology, Boston University School of Medicine, Boston Medical Center, Boston, MA, United States.
Xuesong BaiDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Liqun JiaoDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Wen-Huo ChenDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Endovascular treatment (EVT) is a standard therapy for acute ischemic stroke (AIS) caused by large vessel occlusion (LVO). However, the performance of EVT in primary stroke centers (PSCs) in China remains uncertain. This study aims to explore the performance of EVT in PSCs and compare it with that in comprehensive stroke centers (CSCs). Methods: We conducted a prospective registry of EVT at 11 CSCs and 26 PSCs in China. AIS patients with intracranial LVO who received EVT were divided into two groups based on the type of stroke center. We compared the AIS workflow, EVT procedural details, radiological, and clinical outcomes between the two groups. Results: From November 2021 to December 2022, 1,196 patients were enrolled, and 847 were included in the analysis. Overall, 84.8% of patients achieved successful reperfusion, and 46.3% achieved good clinical outcomes. Compared with patients treated at CSCs, those treated at PSCs had shorter onset-to-presentation time (OPT: 152 min vs. 268 min, Conclusion: In China, successful reperfusion rates were lower and mortality rates were higher despite shorter onset-to-presentation times in primary stroke centers. Additionally, door-to-puncture times were prolonged despite limited use of advanced brain imaging. These findings highlight the need for EVT skill training and improvement in the AIS workflow in primary stroke centers to enhance patient outcomes.

Indexed as

acute ischemiacomprehensive stroke centerendovascular treatmentlarge vessel occlusionprimary stroke centerprognosis

Identifiers

PMID41293410
PMCPMC12641255

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.