ArticleClinical case reports2025
Unusual White Plaques on the Tongue in a 37-Year-Old Male.
Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Unusual White Plaques on the Tongue in a 37-Year-Old Male.Clinical case reports · 2025Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frictional keratosis is a benign reactive condition of the oral mucosa resulting from chronic mechanical irritation. This case report describes a 37-year-old male presenting with asymptomatic, bilateral, non-removable white plaques on the lateral borders of the tongue. Clinical examination, medical history, and lesion morphology ruled out infectious and neoplastic conditions, leading to a provisional diagnosis of frictional keratosis associated with the use of orthodontic clear aligners. Discontinuation of aligner use resulted in complete lesion resolution within 21 days, confirming the diagnosis without the need for invasive diagnostic procedures. This case highlights the importance of recognizing orthodontic appliances, particularly clear aligners, as potential sources of frictional trauma. Prompt identification and elimination of the irritant are essential to avoid unnecessary interventions. To the best of our knowledge, this is the first reported case of frictional keratosis linked to orthodontic clear aligners.
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