The Two-Hand Approach to Retrograde Intubation.

Retrograde intubation is a minimally invasive and underutilized airway rescue technique that bypasses the need for direct visualization of the vocal cords by passing a guidewire from the cricothyroid membrane to the nasopharynx or oropharynx, creating a pathway for an endotracheal tube (ETT) into the trachea. This technique is particularly valuable in difficult airway scenarios such as bleeding, edema, distorted anatomy, maxillofacial trauma, or cervical spine immobility, and utilizes simple equipment and common anatomical landmarks, making it efficient for emergency or resource-limited settings. The standard procedure involves puncturing the cricothyroid membrane with a needle, advancing the guidewire cephalad, guiding an airway exchange catheter over the guidewire, threading the ETT over the catheter, and removing the guidewire and catheter. However, a major challenge is dislodgment of the catheter from its subglottic position. The two-hand modification addresses this problem by having the operator stabilize the ETT at the nares with one hand while securing the airway exchange catheter with the other, allowing controlled movement and minimizing displacement during guidewire and catheter withdrawal. While complications such as bleeding, subcutaneous emphysema, pneumomediastinum, infection, guidewire or catheter kinking, and vocal cord trauma can occur, these risks can be mitigated by using the two-hand modification combined with tools such as suction, video laryngoscopy, and fiberoptic scopes, making retrograde intubation with the two-hand approach a reliable, lifesaving technique that provides improved stabilization, reduced complications, and increased success rates for difficult airway management.