Evidence map›Paper›PMID 41293338›Full record

ArticleCureus2025

Conformable Endovascular Aneurysm Repair (EVAR) Stability in Hostile Neck Abdominal Aortic Aneurysms: A Single-Center Experience.

Ayman Zyada, Rutwik Hegde, Mohamed Eltayeb Abdelrahman Naiem, Bryce Renwick

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ayman ZyadaVascular Surgery, Aberdeen Royal Infirmary, Aberdeen, GBR.
Rutwik HegdeVascular Surgery, Aberdeen Royal Infirmary, Aberdeen, GBR.
Mohamed Eltayeb Abdelrahman NaiemVascular Surgery, Aberdeen Royal Infirmary, Aberdeen, GBR.
Bryce RenwickVascular Surgery, Aberdeen Royal Infirmary, Aberdeen, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Stent graft migration is a well-recognized complication of endovascular aneurysm repair (EVAR) that can predispose patients to type I endoleaks, renal artery compromise, and secondary interventions, particularly in cases with hostile neck anatomy, which poses a significant technical challenge for graft fixation. The GORE Excluder Conformable AAA Endoprosthesis (CLEVAR) is specifically designed to address these challenges by accommodating neck lengths as short as 10 mm, diameters down to 16 mm, and angulations up to 90°. This study aimed to evaluate the early stability and safety of the CLEVAR in patients with hostile neck anatomy by assessing its migration behavior within the first postoperative year. Methodology This retrospective, single-center study analyzed consecutive patients who underwent repair of hostile neck abdominal aortic aneurysms with the CLEVAR device between January 2019 and December 2022, focusing on early (≤1 year) postoperative stability. Eligible patients completed both three-month and one-year postoperative CT angiography. Migration was assessed by measuring the distance between the proximal stent edge and the bilateral renal arteries at both time points, with the difference representing stent movement. Descriptive statistics were calculated, normality was tested using the Shapiro-Wilk method, and comparisons were performed with nonparametric Wilcoxon signed-rank tests. Results A total of 25 patients were included. The mean stent migration across the cohort was 1.29 mm (SD 1.36 mm), with a median of 0.85 mm and a maximum migration of 6.0 mm. Both right and left renal reference points showed similar results (mean 1.17 mm and 1.40 mm, respectively), with no statistically significant difference between sides (p = 0.4261). Migration distributions were non-normally distributed and positively skewed. Analysis confirmed that stent displacement was statistically greater than zero (p < 0.00000001), indicating measurable, albeit small, positional changes during the interval. Conclusions In this study, the CLEVAR device demonstrated stable proximal fixation in challenging hostile neck anatomies over the first postoperative year. Observed migration was minimal, symmetrical, and well below thresholds considered clinically significant. These findings suggest that CLEVAR provides reliable early stability in anatomically complex aneurysm necks, potentially reducing the risk of migration-associated complications. However, the small sample size, retrospective design, and one-year follow-up limit generalizability. Longer-term studies with larger cohorts are needed to confirm the durability of fixation and explore the relationship between late migration, endoleak incidence, and the need for reintervention.

Indexed as

abdominal aortic aneurysmaortic endograft stabilityendovascular aneurysm repairendovascular reinterventiongore excluder conformablehostile neck anatomyproximal fixationstent graft migration

Identifiers

PMID41293338
PMCPMC12643121

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.