Evidence map›Paper›PMID 41293306›Full record

ArticleACG case reports journal2025

Endoscopic Resection of an Esophageal Gastrointestinal Stromal Tumor After Neoadjuvant Treatment: A New Paradigm for Minimally Invasive Therapy?

Fabian Dario Rodriguez-Monaco, Maximilian Herter, Dolores Krauss, Hans Fuchs, Tomasz Zienkiewicz, Franz Ludwig Dumoulin

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fabian Dario Rodriguez-MonacoDepartment of Medicine/Gastroenterology, Gemeinschaftskrankenhaus Bonn, Bonn, Germany.
Maximilian HerterDepartment of Medicine/Gastroenterology, Gemeinschaftskrankenhaus Bonn, Bonn, Germany.
Dolores KraussDepartment for General, Visceral, Thoracic and Transplantation Surgery, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Hans FuchsDepartment for General, Visceral, Thoracic and Transplantation Surgery, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Tomasz ZienkiewiczMVZ for Pathology/Molecular Pathology Bonn, Bonn, Germany.
Franz Ludwig DumoulinDepartment of Medicine/Gastroenterology, Gemeinschaftskrankenhaus Bonn, Bonn, Germany.ORCID https://orcid.org/0000-0002-1058-7867

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal gastrointestinal stromal tumors (eGISTs) are rare. Current guidelines recommend surgical R0 resection. Here, we report on a patient diagnosed with a larger (>30 mm) localized GIST in the midesophagus. After interdisciplinary discussion and discussion with the patient, we initiated a neoadjuvant therapy with imatinib 400 mg. The tumor was downsized and removed uneventfully by endoscopic tunneling resection. Histopathology showed a 19 × 18 × 17 mm ypT1-R1 eGIST. After shared decision-making, the patient continues therapy with imatinib and is in remission 1 year after resection. Downsizing by neoadjuvant treatment could increase the number of endoscopically resectable eGISTs.

Indexed as

gastrointestinal stromal tumorGISTneoadjuvant therapySTERsubmucosal tunnel endoscopic resection

Identifiers

PMID41293306
PMCPMC12643604

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.