Evidence map›Paper›PMID 41293304›Full record

ArticleACG case reports journal2025

A Case of Sweet Syndrome Complicating Ulcerative Colitis Treated With Upadacitinib.

Sankirth Madabhushi, Sarah Dixon, May Dong, Nicole Lewandrowski, Zendee Elaba, Jessica St John, Andrea Poisson Irani, Abbas Rupawala

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sankirth MadabhushiDepartment of Medicine, UMass Chan Medical School, Worcester, MA.ORCID https://orcid.org/0009-0002-6643-2415
Sarah DixonSchool of Medicine, University of Galway, Galway, Ireland.
May DongDepartment of Medicine, UMass Chan Medical School, Worcester, MA.
Nicole LewandrowskiDepartment of Pathology, UMass Chan Medical School, Worcester, MA.
Zendee ElabaDepartment of Pathology, UMass Chan Medical School, Worcester, MA.
Jessica St JohnDepartment of Dermatology, UMass Chan Medical School, Worcester, MA.
Andrea Poisson IraniDepartment of Medicine, UMass Chan Medical School, Worcester, MA.
Abbas RupawalaDivision of Gastroenterology, UMass Chan Medical School, Worcester, MA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is a rare inflammatory skin condition characterized by the sudden onset of painful, erythematous papules and plaques. It has been associated with underlying inflammatory bowel disease. We present a 24-year-old man with recently diagnosed ulcerative colitis on infliximab and methotrexate who was diagnosed by biopsy with Sweet syndrome. The patient was treated with multiple trials of steroids and biologics until finally showing improvement with upadacitinib. This case highlights the importance of considering Sweet syndrome in ulcerative colitis patients with atypical skin manifestations and the first documented case of Sweet syndrome treated with upadacitinib.

Indexed as

inflammatory bowel diseaseSweet syndromeulcerative colitisupadacitinib

Identifiers

PMID41293304
PMCPMC12643761

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.