Evidence map›Paper›PMID 41293294›Full record

ArticleRSC advances2025

Ion-paired antibiotics in PLGA nanoparticles: improving encapsulation efficiency and musculoskeletal infection treatment.

Vladislav Frolov, Tamás Sovány, Jan Loskot, Edit Csapó, Norbert Varga, Alharith A A Hassan, Ondřej Janďourek, Klára Konečná, Aleš Bezrouk, Eva Šnejdrová

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vladislav FrolovDepartment of Pharmaceutical Technology, Faculty of Pharmacy in Hradec Králové, Charles University Akademika Heyrovského 1203 500 05 Hradec Králové Czech Republic frolovv@faf.cuni.cz.ORCID https://orcid.org/0009-0009-8016-4016
Tamás SoványInstitute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged Eötvös u. 6. H-6720 Szeged Hungary.
Jan LoskotDepartment of Medical Biophysics, Faculty of Medicine in Hradec Králové, Charles University 500 03 Hradec Králové Czech Republic.ORCID https://orcid.org/0000-0003-0172-4353
Edit CsapóMTA-SZTE Lendület "Momentum" Noble Metal Nanostructures Research Group, University of Szeged Rerrich B. sq. 1 H-6720 Szeged Hungary.
Norbert VargaMTA-SZTE Lendület "Momentum" Noble Metal Nanostructures Research Group, University of Szeged Rerrich B. sq. 1 H-6720 Szeged Hungary.
Alharith A A HassanInstitute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged Eötvös u. 6. H-6720 Szeged Hungary.
Ondřej JanďourekDepartment of Biological and Medical Sciences, Faculty of Pharmacy in Hradec Kralove, Charles University Akademika Heyrovského 1203 500 05 Hradec Kralove Czech Republic.ORCID https://orcid.org/0000-0003-4633-2062
Klára KonečnáDepartment of Biological and Medical Sciences, Faculty of Pharmacy in Hradec Kralove, Charles University Akademika Heyrovského 1203 500 05 Hradec Kralove Czech Republic.
Aleš BezroukDepartment of Medical Biophysics, Faculty of Medicine in Hradec Králové, Charles University 500 03 Hradec Králové Czech Republic.ORCID https://orcid.org/0000-0002-2397-3847
Eva ŠnejdrováDepartment of Pharmaceutical Technology, Faculty of Pharmacy in Hradec Králové, Charles University Akademika Heyrovského 1203 500 05 Hradec Králové Czech Republic frolovv@faf.cuni.cz.ORCID https://orcid.org/0000-0001-8788-5603

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many studies have shown that gentamicin (GEN) and vancomycin (VAN) are effective in the treatment of musculoskeletal infections, especially when applied locally in the form of sustained-release drug delivery systems. A promising strategy in this area appears to be the impregnation of allogeneic bone grafts with antibiotics loaded poly(d,l-lactide-

Identifiers

PMID41293294
PMCPMC12643545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.