Estimation of habitual intake of infrequently consumed nutrients using the mixture distribution method.

Background: The habitual intake of infrequently consumed nutrients typically exhibits a highly skewed distribution, primarily driven by the reported consumption and non-consumption of nutrients in repeated 24-h dietary recalls. The current methods for estimating this distribution are often computationally intense. Methods: A mixture distribution method (MDM) was proposed to estimate habitual intake distribution of infrequently consumed nutrients, in which the frequency of consumption of a nutrient was modeled using a beta-binomial distribution and the amount consumed using a gamma distribution. The habitual intake using this method was compared to the Iowa State University Foods (ISUF) method using sample data consisting of four non-consecutive 24-h diet recalls collected from 120 children aged 6-59 months in Bihar, India. To assess the impact of zero inflation on the estimation of habitual intake, nutrient intakes were simulated with varying percentages of positive intakes, and habitual intakes were calculated using both methods. Results: The median (IQR) habitual intakes estimated from the MDM and ISUF methods were 0.47 mg (0.29, 0.65) and 0.46 mg (0.29, 0.62) for vitamin B Discussion: The proposed MDM offers a computationally simpler approach to estimate habitual intake distribution by modeling the probability distribution of non-consumption and the distribution of positive intakes. The procedure can be easily implemented using standard statistical software and estimates habitual intake for infrequently consumed nutrients from multiple 24-h dietary recalls.