Long Duration Ultrasound: Recent Advancements and Clinical Applications.

Sardar Mz Uddin, Ralph Ortiz

Abstract read

In one paragraph

Article in International journal on physical medication & rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Ultrasound-Based Therapies in Primary Central Nervous System Tumors.Cancers · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sardar Mz UddinDepartment of Orthopaedics and Rehabilitation, Stony Brook University, Stony Brook, USA.

Ralph OrtizDepartment of Pain Management, Cayuga Medical Center, USA.

Funding

Self-Applied Wearable Ultrasound Therapy for Osteoarthritis Management in Rural CR43MD008597 · NIMHD · ZETROZ, INC. · PI LEWIS, GEORGE KENNETH · 2013 to 2014

$397k

NIMHD NIH HHS R43 MD008597

6 · The paper itself

Abstract

Long-duration low-intensity ultrasound (LDUS) delivers acoustic waves producing localized mechanical and thermal stimuli that modulate cellular and extracellular processes. These stimuli activate mechano transduction pathways, alter extracellular matrix structure, and enhance vascular and metabolic activity, enabling LDUS to serve as a non-invasive therapeutic modality across various clinical domains), particularly through the FDA-approved Sustained Acoustic Medicine (SAM) device, deliver continuous ultrasound at 3 MHz and 132 mW/cm

Indexed as

Blood CirculationDiathermiaDrug DeliveryLong-Duration Low-Intensity UltrasoundPhysical Therapy

Identifiers

PMID41293133

PMCPMC12642968

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.