ArticleRSC advances2025
A continuous flow process for the Ireland-Claisen rearrangement.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Herein, we describe an in-depth study of an enantioselective Ireland-Claisen rearrangement using a continuous flow reactor. The use of this innovative technology led to a rapid reaction at room temperature, enabling the stereocontrolled synthesis of vicinal stereogenic centers with little to no loss in yield or optical purity, in the absence of cryogenic conditions. The reaction scope was examined
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.