ReviewFrontiers in neuroscience2025
The role of prefrontal-hippocampal functional connectivity in schizophrenia-related cognitive dysfunction and the thalamic ventral midline involvement:
Review in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- From synapse to system: mechanistic pathways of neural signaling dysfunction in psychiatric disorders.Frontiers in cell and developmental biology · 2026Review
- Association Between Frontotemporal Atrophy and Cognitive Impairment in Patients with Schizophrenia Based on Computed Tomography Imaging.Neuropsychiatric disease and treatment · 2026Article
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Authors and funding
2 authors.
Funding
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Abstract
Schizophrenia (SCZ) is a multiform psychiatric disorder in which impairments of high-order cognitive abilities, such as flexibility, working memory, and decision-making, are considered onset markers. These deficits are associated with dysfunctions in the prefrontal cortex (PFC) and hippocampus (HPC), two brain regions that play crucial roles in higher-order cognitive processes. While the roles of the PFC and HPC in SCZ have been widely studied, the interaction between these regions and their contributions to the observed cognitive deficits, in conjunction with other intermediate structures, refMRI connectivity as a biomarker main poorly understood. This paper primarily aims to create a hypothesis-generating framework in the context of PFC-HPC altered communication and intermediate structures that may contribute to cognitive impairments in psychosis-related conditions. Here, we present several testable hypotheses concerning the role of specific actors (e.g., GABAergic Parvalbumin-positive interneurons, thalamic calcium signaling channels) in the PFC-HPC connectivity. By presenting evidence from
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