Evidence map›Paper›PMID 41293089›Full record

ArticleInternational journal of cardiology. Cardiovascular risk and prevention2025

Prevalence, associated factors, and prognostic value of P wave abnormality in patients with coronary artery disease.

Kazutoshi Hirose, Hiroyuki Kiriyama, Shun Minatsuki, Yugo Nagae, Tatsuki Furusawa, Takashi Hiruma, Atsushi Kobayashi, Masataka Sato, Shinnosuke Sawano, Tatsuya Kamon and 6 more

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Article in International journal of cardiology. Cardiovascular risk and prevention, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kazutoshi HiroseDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Hiroyuki KiriyamaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Shun MinatsukiDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Yugo NagaeDepartment of Healthcare Information Management, The University of Tokyo, Tokyo, Japan.
Tatsuki FurusawaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Takashi HirumaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Atsushi KobayashiDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Masataka SatoDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Shinnosuke SawanoDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Tatsuya KamonDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Hiroki ShinoharaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Akihito SaitoDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Satoshi KoderaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Junichi IshidaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Hiroyuki MoritaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Norihiko TakedaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: P-wave terminal force in V1 (PTFV1) on electrocardiography is an easily available and cost-effective surrogate marker reflecting myocardial electrical and structural remodeling. An abnormal PTFV1 was recently suggested to be a reliable predictor of adverse cardiovascular events, whereas its performance in the setting of coronary artery disease (CAD) remains unknown. Methods: We retrospectively investigated 3147 patients with CAD who underwent percutaneous coronary intervention at our institution. Abnormal PTFV1 was defined as PTFV1 >0.04 mm⋅s. The primary outcome was a composite of cardiac death and heart failure hospitalization. The Cox proportional hazard models were constructed to investigate the association between PTFV1 and clinical outcome. Results: Among the study population, 592 (18.8 %) patients had abnormal PTFV1. Patients with abnormal PTFV1 had worse atherosclerotic and cardiovascular profiles, higher concentrations of brain natriuretic peptide and C-reactive protein, and more advanced CAD than those with normal PTFV1 (p < 0.05). The abnormal PTFV1 group had more pronounced left ventricular and atrial remodeling than normal PTFV1 group (p < 0.05), but the association between left atrial size and PTFV1 was not significant after multivariable adjustment (p = 0.355). During a median follow-up of 5.2 years, patients with abnormal PTFV1 more frequently experienced the primary outcome than those with normal PTFV1 (log-rank p < 0.001). Abnormal PTFV1 carried a significant risk for the primary outcome independent of baseline characteristics, biomarkers, and angiographic features (adjusted hazard ratio 2.38, p < 0.001). Conclusions: In patients with CAD who undergo percutaneous coronary intervention, abnormal PTFV1 is a robust and independent risk factor for adverse cardiovascular outcomes.

Indexed as

Cardiovascular outcomeCoronary artery diseasePercutaneous coronary interventionPrognostic valueP-wave terminal force in V1

Identifiers

PMID41293089
PMCPMC12641559

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.