Evidence map›Paper›PMID 41292927›Full record

ArticlebioRxiv : the preprint server for biology2025

Parsing auditory neural code into maximum-entropy packets.

Huanqiu Zhang, Israel Nelken, Tatyana Sharpee

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Huanqiu ZhangNeurosciences Graduate Program, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0009-0006-3773-2944
Israel NelkenThe Edmond and Lily Safra Center for Brain Sciences, Hebrew University of Jerusalem, Jerusalem, Israel.ORCID 0000-0002-6645-107X
Tatyana SharpeeNeurosciences Graduate Program, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-7483-5081

Funding

Spinal Circuits for the Control of Dextrous MovementU19NS112959 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI GOULDING, MARTYN D · 2019 to 2023
$14.3M
San Diego Nathan Shock CenterP30AG068635 · NIA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI SHADEL, GERALD · 2020 to 2024
$6.0M
NIA NIH HHS P30 AG068635NINDS NIH HHS U19 NS112959
6 · The paper itself

Abstract

Deciphering the neural code requires identifying its fundamental symbols or codewords. Neural activity is usually interpreted either as a rate code - based on average spike counts - or as a temporal code, which distinguishes patterns with identical counts. Yet, the symbols of the code remain undefined. Here we show that the symbols can be clearly defined by parsing auditory spike trains into variable-duration "packets", within which precise spike timing is irrelevant. Because packets vary in duration, this is not a rate code. A single neuron could encode very different stimuli depending on the number of spikes it produced per packet. The packet-based code enables real-time readout upon packet completion due to its instantaneous code structure and maximizes information capacity at both single-neuron and population levels.

Identifiers

PMID41292927
PMCPMC12642687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.