Evidence map›Paper›PMID 41292919›Full record

ArticlebioRxiv : the preprint server for biology2025

CASPULE: A computational tool to study sticker spacer polymer condensates.

Aniruddha Chattaraj, David S Kanovich, Srivastav Ranganathan, Eugene I Shakhnovich

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Aniruddha ChattarajDepartment of Chemistry and Chemical Biology, Harvard University, MA 02138, USA.ORCID 0000-0002-7105-6621
David S KanovichDepartment of Chemistry and Chemical Biology, Harvard University, MA 02138, USA.
Srivastav RanganathanDepartment of Chemistry and Chemical Biology, Harvard University, MA 02138, USA.
Eugene I ShakhnovichDepartment of Chemistry and Chemical Biology, Harvard University, MA 02138, USA.

Funding

Biophysical foundations of evolutionary dynamicsR35GM139571 · NIGMS · HARVARD UNIVERSITY · PI SHAKHNOVICH, EUGENE I · 2021 to 2025
$3.9M
NIGMS NIH HHS R35 GM139571
6 · The paper itself

Abstract

Phase separated condensates are recognized as a ubiquitous mechanism of spatial organization in cell biology. Biophysical modeling of condensates provides critical insights into the dynamics and functions of these subcellular structures that are difficult to extract via experiments. Here we present an efficient computational pipeline, CASPULE (

Identifiers

PMID41292919
PMCPMC12642634

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.