Evidence map›Paper›PMID 41292895›Full record

ArticlebioRxiv : the preprint server for biology2025

"Seipin mediates Perilipin-1 recruitment to lipid droplets to preserve human adipocyte identity".

Denise Zhong, Ioanna Stavrakaki, Anand Desai, Tiffany DeSouza, Sabine Linskey, Shannon Joyce, Courtney Hatton, Danna Garcia, Reyan Kassam, Gregory Hendricks and 8 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Denise ZhongProgram in Molecular Medicine.ORCID 0009-0005-1859-6521
Ioanna StavrakakiProgram in Molecular Medicine.ORCID 0009-0006-9830-5508
Anand DesaiProgram in Molecular Medicine.ORCID 0000-0002-3366-0801
Tiffany DeSouzaProgram in Molecular Medicine.ORCID 0000-0001-6237-1139
Sabine LinskeyProgram in Molecular Medicine.ORCID 0000-0002-6935-5649
Shannon JoyceProgram in Molecular Medicine.ORCID 0000-0003-3729-0454
Courtney HattonProgram in Molecular Medicine.ORCID 0000-0002-4387-4782
Danna GarciaProgram in Molecular Medicine.
Reyan KassamProgram in Molecular Medicine.
Gregory HendricksUMass Chan Electron Microscopy Core.
Keith ReddigUMass Chan Electron Microscopy Core.
Guangping GaoThe Li Weibo Institute for Rare Diseases research.ORCID 0000-0003-0097-9012
Jun XieThe Li Weibo Institute for Rare Diseases research.
Maria Paz Gonzalez-PerezUMass Chan Mass Spectrometry Facility.
Andre F C VieiraUMass Chan Mass Spectrometry Facility.ORCID 0009-0008-4157-0145
Caroline L ChidleyProgram in Molecular Medicine.ORCID 0000-0003-1787-5084
John A HaleyProgram in Molecular Medicine.ORCID 0000-0003-2652-4841
Silvia CorveraProgram in Molecular Medicine.ORCID 0000-0002-0009-4129

Funding

Mechanisms of human adipose tissue development and impact of diabetesR01DK123028 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Silvia Corvera · 2019 to 2026
$3.6M
Human adipose tissue in control of sympathetic tone and metabolic rateR01DK137403 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Silvia Corvera · 2023 to 2026
$2.9M
NIDDK NIH HHS R01 DK123028NIDDK NIH HHS R01 DK137403
6 · The paper itself

Abstract

Congenital generalized lipodystrophy type 2 (CGL2) is caused by mutations in the

Identifiers

PMID41292895
PMCPMC12642227

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.