Evidence map›Paper›PMID 41292871›Full record

ArticlebioRxiv : the preprint server for biology2025

MLT-11 is necessary for

James Matthew Ragle, Ariela Turzo, Anton Jackson, An A Vo, Vivian T Pham, Keya Daly, John C Clancy, Max T Levenson, Alex D Lee, Jordan D Ward

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

James Matthew RagleDepartment of Molecular, Cell, and Developmental Biology, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0002-6626-2615
Ariela TurzoDepartment of Molecular, Cell, and Developmental Biology, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
Anton JacksonDepartment of Molecular, Cell, and Developmental Biology, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
An A VoDepartment of Molecular, Cell, and Developmental Biology, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
Vivian T PhamDepartment of Molecular, Cell, and Developmental Biology, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
Keya DalyDepartment of Molecular, Cell, and Developmental Biology, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
John C ClancyDepartment of Molecular, Cell, and Developmental Biology, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0003-2867-9740
Max T LevensonDepartment of Molecular, Cell, and Developmental Biology, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
Alex D LeeDepartment of Molecular, Cell, and Developmental Biology, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
Jordan D WardDepartment of Molecular, Cell, and Developmental Biology, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0001-9870-8936

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Mechanisms of nematode moltingR01GM138701 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI WARD, JORDAN DAVID · 2020 to 2024
$1.6M
Mechanisms of nematode moltingR35GM158317 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Jordan David Ward · 2025 to 2026
$764k
Transcriptional networks controlling molting in C. elegans and B. malayiR00GM107345 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI WARD, JORDAN DAVID · 2017 to 2019
$747k
NIGMS NIH HHS R00 GM107345NIGMS NIH HHS R01 GM138701NIGMS NIH HHS R35 GM158317NIH HHS P40 OD010440
6 · The paper itself

Abstract

Apical extracellular matrices (aECMs) are associated with many epithelia and many form a protective layer against biotic and abiotic threats in the environment. Despite their importance, we lack a deep understanding of their structure and dynamics in development and disease.

Indexed as

Animaliaapical extracellular matrixC. elegansembryogenesisgene regulationmoltingnuclear hormone receptorprotease inhibitor

Identifiers

PMID41292871
PMCPMC12642537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.