Evidence map›Paper›PMID 41292808›Full record

ArticlebioRxiv : the preprint server for biology2025

Learning-dependent cholinergic plasticity reconfigures cortical circuit dynamics.

Andrew H Moberly, Jessica A Cardin, Michael J Higley

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrew H MoberlyDept. of Neuroscience, Yale University, New Haven, CT.
Jessica A CardinDept. of Neuroscience, Yale University, New Haven, CT.
Michael J HigleyDept. of Neuroscience, Yale University, New Haven, CT.

Funding

Bridging cellular and systems neuroscience: synaptic dynamics underlying behaviorDP1EY033975 · NEI · YALE UNIVERSITY · PI HIGLEY, MICHAEL JAMES · 2021 to 2025
$5.9M
Cellular mechanisms of GABAergic inhibition in neocortical dendritesR01MH099045 · NIMH · YALE UNIVERSITY · PI Michael James Higley · 2012 to 2026
$5.7M
Inhibitory regulation of cortical visual processingR01EY022951 · NEI · YALE UNIVERSITY · PI CARDIN, JESSICA A · 2013 to 2025
$4.0M
Role of GABAergic interneurons in developmental dysregulation of cortical functionR01MH113852 · NIMH · YALE UNIVERSITY · PI CARDIN, JESSICA A, HIGLEY, MICHAEL JAMES · 2017 to 2021
$2.1M
Experience-dependent plasticity of circuit dynamicsR01EY035127 · NEI · YALE UNIVERSITY · PI JESSICA A CARDIN · 2024 to 2026
$1.6M
Behavior-dependent classification of neocortical cell typesR21MH121841 · NIMH · YALE UNIVERSITY · PI HIGLEY, MICHAEL JAMES · 2020 to 2021
$461k
Fear learning-related reconfiguration of local and large-scale cortical networksK99EY035344 · NEI · YALE UNIVERSITY · PI MOBERLY, ANDREW · 2023 to 2024
$208k
The role of corticostriatal circuits in visually-guided behaviorF32EY031133 · NEI · YALE UNIVERSITY · PI MOBERLY, ANDREW · 2020 to 2022
$201k
NEI NIH HHS DP1 EY033975NEI NIH HHS F32 EY031133NEI NIH HHS K99 EY035344NEI NIH HHS R01 EY022951NEI NIH HHS R01 EY035127NIMH NIH HHS R01 MH099045NIMH NIH HHS R01 MH113852NIMH NIH HHS R21 MH121841
6 · The paper itself

Abstract

Neuromodulation by acetylcholine (ACh) plays a critical role in reshaping neural dynamics in the neocortex as a function of development, behavioral state, and learning

Identifiers

PMID41292808
PMCPMC12642122

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.