Evidence map›Paper›PMID 41292805›Full record

ArticlebioRxiv : the preprint server for biology2025

Structural and Binding Properties of Dps - A Nucleoid Associated Protein.

Matty Gaines, Daniel Parrell, Kaylee Jo Rajek, Steven Garvis, Bryan Sibert, Elizabeth R Wright

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matty GainesDepartment of Biochemistry, University of Wisconsin, Madison, WI USA.
Daniel ParrellDepartment of Biochemistry, University of Wisconsin, Madison, WI USA.
Kaylee Jo RajekDepartment of Biochemistry, University of Wisconsin, Madison, WI USA.
Steven GarvisDepartment of Biochemistry, University of Wisconsin, Madison, WI USA.
Bryan SibertDepartment of Biochemistry, University of Wisconsin, Madison, WI USA.
Elizabeth R WrightDepartment of Biochemistry, University of Wisconsin, Madison, WI USA.ORCID 0000-0003-0712-9475

Funding

The Midwest Center for Cryo-Electron TomographyU24GM139168 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI WRIGHT, ELIZABETH R · 2020 to 2025
$41.7M
Structure and Function of Prokaryotic Appendages by Cryo-Electron TomographyR01GM104540 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI WRIGHT, ELIZABETH R · 2013 to 2017
$1.4M
Form and function of the bacterial nucleoid: structural studies using cryo-ETF32GM143854 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PARRELL, DANIEL · 2021 to 2022
$136k
NIGMS NIH HHS F32 GM143854NIGMS NIH HHS R01 GM104540NIGMS NIH HHS U24 GM139168
6 · The paper itself

Abstract

Prokaryotic chromosomal DNA is compacted and protected by nucleoid-associated proteins (NAPs). Among these, the DNA-binding proteins from starved cells (Dps) combine ferroxidase activity with nonspecific DNA binding to form dodecameric assemblies that condense and safeguard the genome under stress. Here, we present an integrated structural and biophysical analysis of

Indexed as

cryo-electron microscopy (cryo-EM)cryo-electron tomography (cryo-ET)DNA-binding proteins from starved cells (Dps)Escherichia coli (E. coli)ferritin-like proteinnucleoid-associated protein (NAP)nucleoid compaction

Identifiers

PMID41292805
PMCPMC12642551

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.