Evidence map›Paper›PMID 41292727›Full record

ArticlebioRxiv : the preprint server for biology2025

Heightened empathic responses led by imbalanced cortico-amygdala circuit in

Sheng-Nan Qiao, Yong-Hui Jiang

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sheng-Nan QiaoDepartment of Genetics, Yale University School of Medicine; New Haven, CT, 06510, USA.ORCID 0000-0002-5182-8073
Yong-Hui JiangDepartment of Genetics, Yale University School of Medicine; New Haven, CT, 06510, USA.

Funding

Molecular and circuitry mechanism underlying autism behaviors in Shank3 mouse modelsR01MH117289 · NIMH · YALE UNIVERSITY · PI JIANG, YONG-HUI · 2019 to 2023
$3.2M
Characterizing the (epi)genetics of oxytocin response in clinical and animal modelsR01HD088007 · NICHD · DUKE UNIVERSITY · PI GREGORY, SIMON G, JIANG, YONG-HUI · 2017 to 2021
$2.9M
Analysis of Shank3 Complete and Temporal and Spatial Specific Knockout MiceR01MH098114 · NIMH · DUKE UNIVERSITY · PI JIANG, YONG-HUI · 2012 to 2016
$2.2M
A novel neural circuit analysis paradigm to model autism in miceR21MH104316 · NIMH · DUKE UNIVERSITY · PI JIANG, YONG-HUI · 2014 to 2015
$435k
A novel paradigm to dissect the function connectivity in Shank3 autism modelR21HD087795 · NICHD · YALE UNIVERSITY · PI JIANG, YONG-HUI · 2017 to 2018
$434k
NICHD NIH HHS R01 HD088007NICHD NIH HHS R21 HD087795NIMH NIH HHS R01 MH098114NIMH NIH HHS R01 MH117289NIMH NIH HHS R21 MH104316
6 · The paper itself

Abstract

Affective empathy is defined as individual percept and respond to another emotion appropriately, an essential building block for human society. Historically, aberrant empathy was considered as major characteristics of autistic individuals but recently it has been challenged. It required mechanistic understanding of the empathy process, especially how autistic individual percept other emotion. By evaluating the social fear transfer response, we reported a critical role of

Identifiers

PMID41292727
PMCPMC12642579

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.