Evidence map›Paper›PMID 41292725›Full record

ArticlebioRxiv : the preprint server for biology2025

A self-organizing single-cell morphology circuit optimizes

Zhejing Xu, Lauren E Mazurkiewicz, Marine Olivetta, Marisol Morrissey, Omaya Dudin, Amy M Weeks, Scott M Coyle

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Zhejing XuDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Lauren E MazurkiewiczDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Marine OlivettaDepartment of Biochemistry, Faculty of Sciences, University of Geneva, Geneva, Switzerland.
Marisol MorrisseyDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Omaya DudinDepartment of Biochemistry, Faculty of Sciences, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-6673-3149
Amy M WeeksDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-4700-8256
Scott M CoyleDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-2451-8763

Funding

Biotechnology Training ProgramT32GM135066 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SCOTT M. COYLE, BRIAN G FOX · 2020 to 2026
$7.0M
NIGMS NIH HHS T32 GM135066
6 · The paper itself

Abstract

Cellular structure self-organizes through an interplay between internal mechanisms and external cues. In predatory ciliates, structures that capture prey obtain the resources needed for their construction, creating feedback between environmental inputs and morphological outputs. Here, we describe a self-organizing single-cell morphology circuit that adaptively optimizes the predatory trap structure of the suctorian

Identifiers

PMID41292725
PMCPMC12642228

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.