ReviewFrontiers in microbiology2025
Mobile genetic elements and wastewater treatment: contaminants of emerging concern, climate change, and trophic transmission.
Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Wastewater Metagenomics for Antimicrobial Resistance and Pathogen Surveillance: A Bibliometric Analysis.Microorganisms · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This minireview focuses on recent developments regarding mobile genetic elements (MGEs) and horizontal gene transfer (HGT) in wastewater treatment plants (WWTPs) and proximal environments. WWTPs are often discussed as hotspots and bioreactors for the evolution of MGEs and ARGs and their horizontal transfer. Firstly, the article reviews the effects of emerging contaminants on HGT and MGEs with a specific focus on microplastics and per- and polyfluoroalkyl substances (PFAS). Secondly, the review focuses on how extreme weather and climate change can overwhelm WWTPs, increase the input of diverse genetic elements, and alter the dynamics of HGT. Finally, the trophic connections between the WWTP microbiota and external ecosystems underscore the potential for wider transmission of MGEs. Here, the focus is on transfer of MGEs to larger organisms in the vicinity of WWTPs. In sum, the review focuses on emerging areas of research that refine our understanding of the WWTP environment as a hotspot for HGT and dissemination of MGEs with potentially deleterious implications for human and wider ecosystem health.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.