Evidence map›Paper›PMID 41292658›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Develop and Validate A Fair Machine Learning Model to Indentify Patients with High Care-Continuity in Electronic Health Records Data.

Yao An Lee, Tiange Tang, Yu Huang, Jiang Bian, Lizheng Shi, Jingchuan Guo

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Yao An LeeDepartment of Pharmaceutical Outcomes & Policy, University of Florida, Gainesville, FL, USA.ORCID 0009-0008-3971-4242
Tiange TangDepartment of Health Policy and Management, Celia Scott Weatherhead School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA.
Yu HuangDepartment of Biostatistics & Health Data Science, Indiana University, Indianapolis, IN, USA.ORCID 0000-0001-7373-4716
Jiang BianDepartment of Biostatistics & Health Data Science, Indiana University, Indianapolis, IN, USA.ORCID 0000-0002-2238-5429
Lizheng ShiDepartment of Health Policy and Management, Celia Scott Weatherhead School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA.ORCID 0000-0002-7827-6766
Jingchuan GuoCenter for Biomedical Informatics, Regenstrief Institute, Indianapolis, IN, USA.ORCID 0000-0001-9799-2592

Funding

Supplement of NIDDK R01 newer GLDs and Clinical OutcomesR01DK133465 · NIDDK · UNIVERSITY OF FLORIDA · PI GUO, JINGCHUAN, SHAO, HUI · 2022 to 2025
$2.8M
iSMART: intelligent Social risk Management in AD/ADRD paTientsR01AG089445 · NIA · UNIVERSITY OF FLORIDA · PI Jiang Bian, Jingchuan Guo · 2024 to 2026
$2.2M
NIA NIH HHS R01 AG089445NIDDK NIH HHS R01 DK133465
6 · The paper itself

Abstract

Objectives: Electronic health record (EHR) data often missed care outside a given health system, resulting in data discontinuity. We aimed to: (1) quantify misclassification across levels of EHR data discontinuity and identify an optimal continuity threshold. (2) develop a machine learning (ML) model to predict EHR continuity and optimize fairness across racial and ethnic groups, and (3) externally validate the EHR continuity prediction model using an independent dataset. Materials and Methods: We used linked OneFlorida+ EHR-Medicaid claims data for model development and REACHnet EHR-Louisiana Blue Cross Blue Shield (LABlue) claims data for external validation. A novel Harmonized Encounter Proportion Score (HEPS) was applied to quantify patient-level EHR data continuity and the impact on misclassification of 42 clinical variables. ML models were trained using routinely available demographic, clinical, and healthcare utilization features derived from structured EHR data. Results: Higher EHR data continuity was associated with lower rates of misclassification. A HEPS threshold of approximately 30% effectively distinguished patients with sufficient data continuity. ML models demonstrated strong performance in predicting high continuity (AUROC=0.77). Fairness assessments showed bias against Hispanic group, which was substantially improved following bias mitigation procedures. Model performance remained robust and fair in the external validation. Discussion: Our study offers a practical metric for quantifying care continuity in EHR networks. The current ML model incorporating EHR-routinely collected information can accurately identify patients with high care continuity. Conclusions: We developed a generalizable care-continuity classification tool that can be easily applied across EHR systems, strengthening the rigor of EHR-based research.

Indexed as

Data continuityEHRMachine learning prediction

Identifiers

PMID41292658
PMCPMC12642717

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.