Evidence map›Paper›PMID 41292588›Full record

ArticleFrontiers in bioengineering and biotechnology2025

Preclinical evaluation of 3D-Printed orthodontic aligners using an electro-typodont model.

Ammar A Al Shalabi, Shaima Malik, Hoon Kim, Abdulaziz Alhotan, Ahmed Ghoneima, Tarek M Elshazly

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ammar A Al ShalabiDepartment of Orthodontics and Pediatric Dentistry, Hamdan Bin Mohammed College of Dental Medicine (HBMCDM), Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Dubai, United Arab Emirates.
Shaima MalikDivision of Orthodontics and Dentofacial Orthopedics, Eastman Institute for Oral Health, University of Rochester Eastman Institute for Oral Health, Rochester, NY, United States.
Hoon KimResearch Institute of Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea.
Abdulaziz AlhotanDepartment of Dental Health, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Ahmed GhoneimaDepartment of Orthodontics and Pediatric Dentistry, Hamdan Bin Mohammed College of Dental Medicine (HBMCDM), Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Dubai, United Arab Emirates.
Tarek M ElshazlyDepartment of Orthodontics and Pediatric Dentistry, Hamdan Bin Mohammed College of Dental Medicine (HBMCDM), Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Dubai, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The use of 3D printing in orthodontic aligner production addresses several limitations of conventional thermoforming. However, existing experimental techniques for evaluating aligner efficacy remain restricted. This study aims to introduce a novel experimental approach employing an electric typodont model to assess the effectiveness of 3D-printed orthodontic aligners in correcting rotation of the maxillary right central incisor (Tooth 11). Materials and Methods: An electric typodont, equipped with heat-activated wax blocks, simulated four rotational severities of Tooth 11: 22°, 32°, 42°, and 52°. Digital scans were processed in Maestro 3D software to design virtual treatment plans, from which four sequential aligners were fabricated per severity level. In total, 240 aligners were 3D-printed, using Tera Harz TC-85 resin, in three thicknesses: 0.50, 0.75, and 1.00 mm. Each aligner underwent a 10-minute heating cycle, followed by a 10-min cooling period. Tooth rotation was measured manually using a protractor relative to a fixed baseline. The procedure was repeated five times per subgroup, with repositioning guided by custom guiding stents. Results: Across all aligner thicknesses, 80.0%-93.1% of the planned rotational correction was achieved by the fourth aligner, leaving residual rotations of approximately 4°-5°. Higher initial rotations resulted in a greater percentage of corrections (p < 0.001). The 0.50-mm and 1.00-mm aligners demonstrated faster early-stage correction, whereas the 0.75-mm aligner exhibited a more gradual and consistent derotation pattern throughout the treatment stages (p < 0.001). Conclusion: The electric typodont appears to be a reliable pre-clinical tool for evaluating the effectiveness of aligners. Furthermore, 3D-printed aligners successfully achieved incisor derotation without the use of attachments. Furthermore, while variations in aligner thickness influenced the dynamics of derotation, they did not alter the ultimate correction outcome.

Indexed as

biomechanicsdental modelsorthodontic appliancesorthodonticsprinting

Identifiers

PMID41292588
PMCPMC12641186

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.