ArticleHealth science reports2025
Evaluation of the Frequency and Patterns of Cervical Cancer Recurrence After Treatment Using ^18F-FDG PET-CT: A Cross-Sectional Study.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Comparative Performance of Pap Smear and Colposcopy in Cervical Cancer Screening Among Women With Abnormal Cervical Findings in Central India: A Prospective Observational Study.Health science reports · 2026Article
- Evaluation of the Frequency and Patterns of Cervical Cancer Recurrence After Treatment Using ^18F-FDG PET-CT: A Cross-Sectional Study.Health science reports · 2025Article
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Abstract
Background and Aim: Cervical cancer recurrence remains a major clinical challenge, particularly in patients with advanced disease or high-risk pathological features. This study aimed to evaluate the frequency and distribution of recurrence and metastases in posttreatment cervical cancer patients using ^18F-FDG PET/CT, with additional analysis by histological subtype and primary treatment modality. Methods: This retrospective cross-sectional study included 120 posttreatment cervical cancer patients who underwent ^18F-FDG PET/CT at the Institute of Nuclear Medicine and Oncology, Lahore, Pakistan, between July 2024 and January 2025. Patient demographics, tumor histology, and PET-CT findings were recorded. Recurrence was classified as local, lymphatic, visceral, or skeletal. Data were analyzed using SPSS (v26.0). The Chi-square test compared recurrence patterns between histological subtypes. A Results: The overall recurrence rate was 65.0% ( Conclusion: This study demonstrates that ^18F-FDG PET-CT is a valuable imaging modality for detecting recurrence and metastases in posttreatment cervical cancer patients. The recurrence rate was high, with adenocarcinoma showing a greater risk compared to squamous cell carcinoma. PET-CT effectively identified both local and distant disease, with chest and abdominal nodes, lungs, and liver being the most frequent metastatic sites, while skeletal involvement was rare. Recurrence was also significantly associated with treatment modality, being lowest after surgery and higher among patients treated with chemoradiation or combined therapy.
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