Evidence map›Paper›PMID 41292573›Full record

ArticleHealth science reports2025

Comparative Evaluation of Glycaemic and Non-Glycaemic Factors as Determinants of Retinopathy Status in an Adult Population: A Case-Control Study.

Moses Banyeh, Raymond Buadee, Amy Louisa Anaman, Felix Ofori, Baba Madde Mohammed, Marian Griffin, Emmanuel Kofi Mensah, Gloria Adutwumwaa Sarpong, Cornelius Elikem Fiawotso, Solomon Aweworo Wepia and 13 more

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Moses BanyehDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.ORCID https://orcid.org/0000-0003-3594-6077
Raymond BuadeeDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Amy Louisa AnamanDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Felix OforiDepartment of Biomedical Engineering Toronto Metropolitan University Toronto Ontario Canada.
Baba Madde MohammedDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Marian GriffinDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Emmanuel Kofi MensahDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Gloria Adutwumwaa SarpongDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Cornelius Elikem FiawotsoDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Solomon Aweworo WepiaDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Abdul Salam Abdul FattahDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Ernest Kofi AnnanDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Cornelius NifaaDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Emmanuel Ansah OwusuDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Albert ObengDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Prince Kwaku AyisiDepartment of Medical Diagnostics Kwame Nkrumah University of Science and Technology Kumasi Ghana.
Charles NkansahDepartment of Haematology University for Development Studies Tamale Ghana.ORCID https://orcid.org/0000-0001-6986-9976
Gabriel AbbamDepartment of Haematology University for Development Studies Tamale Ghana.ORCID https://orcid.org/0009-0004-6367-7163
Joshua Anzagra DeryDepartment of Clinical Laboratory St. Mary's Medical Centre Huntington West Virginia USA.
Benjamin N MayeemDepartment of Medical Laboratory Living Waters Hospital Ejisu-krapa Ghana.
Clement Binwatin DagungongDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Amos Tuoyintir YelvielledemDepartment of Biomedical Laboratory Sciences University for Development Studies Tamale Ghana.
Nafiu AmiduDepartment of Clinical Chemistry University for Development Studies Tamale Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Hyperglycemia is a known risk factor for retinopathy. With diabetes cases expected to increase from 366 million in 2011 to 552 million by 2030, the global burden of retinopathy may rise. Given this observation, more attention is focused on glycaemic determinants of retinopathy to the neglect of non-glycaemic factors, particularly in Ghana. However, genetic and environmental variations may highlight the importance of non-glycaemic factors as determinants of retinopathy. Methods: This case-control study was conducted between January and August 2024 at the Emmanuel Eye Medical Center in Accra, Ghana. The study involved 160 participants aged between 34 and 81 years. Of the 160 participants, 80 (50%) were diagnosed with retinopathy. Fasting venous blood samples were collected and analyzed for glycaemic factors, including fasting blood glucose (FBG), glycated hemoglobin (HbA1c), and non-glycaemic factors, including fasting lipids and complete blood count indices. Results: Results showed that the FBG (8.4 ± 2.6 vs. 6.3 ± 1.6, Conclusion: Glycaemic factors are more strongly associated with retinopathy than non-glycaemic factors. Early screening should prioritize glycaemic factors while considering non-glycaemic factors due to genetic and environmental variations in retinopathy development.

Indexed as

determinantsGhanaglycaemicretinopathysex differences

Identifiers

PMID41292573
PMCPMC12641152

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.