Trial reportAnales del sistema sanitario de Navarra2025
[Differential effects of computerized cognitive stimulation versus stimulating leisure activities on mood and global cognition in adults with subjective and mild cognitive impairment: A randomized controlled trial].
Trial report in Anales del sistema sanitario de Navarra, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- [Long-term maintenance of the emotional benefits of cognitive stimulation in early-stage cognitive impairment].Anales del sistema sanitario de Navarra · 2026Trial
- [Early detection and active intervention in cognitive decline: A healthcare challenge].Anales del sistema sanitario de Navarra · 2026Article
- [Primary care research: The science of proximity - How can we transform everyday practice into a driver of scientific progress?]Anales del sistema sanitario de Navarra · 2026Article
- [Anales del Sistema Sanitario de Navarra in 2025: Progress continues].Anales del sistema sanitario de Navarra · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMild Cognitive Impairment (MCI) involves both subjective and objective cognitive decline with relatively preserved daily functioning, whereas Subjective Cognitive Impairment (SCI) refers to perceived decline without measurable deficits. This study aimed to compare the effects of a personalized computerized cognitive stimulation (CS) program (IG1) and a stimulating leisure activities program (IG2) in adults with MCI and SCI.
methodsA single-blind randomized controlled trial was conducted in primary care with participants aged =50 years with SCI or MCI. Participants were randomized to IG1, IG2), or a control group (CG). IG1 completed personalized computerized CS for 30 minutes/day, 5 days/week, for 8 weeks. IG2 engaged in 2-5 stimulating leisure activities per week for the same period. The primary outcome was global cognition; secondary outcomes included memory, verbal fluency, daily functioning, and mood.
resultsFifty-nine participants were enrolled in the study, 44 with SCI and 15 with MCI. Compared to CG, IG1 showed greater reductions in anxiety post-intervention (2.07; 95%CI: 0.93-3.22 vs. 4.34; 95%CI: 3.22-5.46) and lower depressive symptoms at 6-month follow-up (3.41; 95%CI: 2.05-4.77 vs. 5.62; 95%CI: 4.26-6.97). IG2 participants demonstrated improved global cognition post-intervention (29.2; 95%CI: 27.625-30.776) and at 6 months (28.78; 95%CI: 27.16-30.42) relative to CG (30.626; 95%CI: 28.99-32.27).
conclusionPersonalized computerized CS reduces anxiety and depression symptoms, while stimulating leisure activities enhances global cognition in community-dwelling adults with SCI and MCI, suggesting complementary benefits of both interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.