Trial reportEuropean journal of medical research2025
Patient-specific vs. Oxford microplasty instrumentation in unicompartmental knee arthroplasty: a randomized controlled trial.
Trial report in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Patient-Specific Instrumentation Improves Technical Execution Accuracy After Artificial Intelligence-Assisted Preoperative Planning in Medial Unicompartmental Knee Arthroplasty.International orthopaedics · 2026Trial
- Three dimensional printing in unicompartmental knee arthroplasty: current evidence and future directions.International orthopaedics · 2026Review
- A narrative review of clinical research on knee osteoarthritis in 2025.Annals of joint · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundThe success of unicompartmental knee arthroplasty (UKA) in treating end-stage knee osteoarthritis is mainly based on the surgical instruments and surgeon's experience. The purpose of this randomized controlled trial was to compare the efficacy of patient-specific instrumentation (PSI) assisted UKA by inexperienced surgeon on the learning curve with conventional Oxford microplasty instrumentation (MPI) assisted UKA.
methodsWe performed a prospective study at a single high-volume orthopaedic hospital. Patients with end-stage medial tibiofemoral osteoarthritis were assessed for eligibility and randomly assigned to undergo either PSI-assisted UKA performed by inexperienced surgeons (PSI group) or MPI-assisted UKA performed by experienced surgeons (MPI group) at a 1:1 ratio. The primary outcome was the femoral varus/valgus angle using the mean score on the first day after surgery. The secondary outcomes included the femoral prosthesis flexion/extension angle, tibial varus/valgus angle, tibial posterior slope angle, and the hip-knee-ankle angle (HKAA). The Knee Society Score (KSS) and Hospital for Special Surgery (HSS) score were assessed at one, three, six, and 12 months. Mixed-effects modelling was used to analyze repeated measurements.
resultsA total of 73 participants (37 in the PSI group and 36 in the MPI group) were enrolled from June 2021 to July 2023. No patients were lost to follow-up. No significant between-group differences were found in the femoral component varus and valgus angle, flexion and extension angle, tibial component varus and valgus angle, tibial posterior slope angle, or hip-knee-ankle angle (all P > 0.05). At the 12-month follow-up, the PSI group and MPI group achieved mean KSSs of 93.4 points (95% CI, 88.6-97.8) and 93.6 points (95% CI, 89.1-98.4), respectively. There were no significant between-group differences in the KSS and HSS score improvements from baseline to each follow-up point.
conclusionsThe PSI-assisted UKA performed by inexperienced surgeon on a learning curve can yield excellent radiographic and functional outcomes in short-term follow-up, despite not demonstrating superior clinical outcomes to MPI-assisted UKA performed by an experienced surgeon. The PSI could potentially serve as an alternative instrumentation for UKA beginners with low-volume surgical caseload.
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