Evidence map›Paper›PMID 41291811›Full record

ArticleBMC chemistry2025

Exploring 1,3,4-oxadiazolyl sulfide derivatives as antidiabetic candidates: synthesis, antioxidant activity, SAR-study, molecular docking, and DFT-insights.

Norhan A Khalaf, Gehad E Said, Ehab Abdel-Latif, Heba M Metwally

Abstract read
In one paragraph

Article in BMC chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Norhan A KhalafDepartment of Chemistry, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.
Gehad E SaidDepartment of Chemistry, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt. gehadsaid@mans.edu.eg.
Ehab Abdel-LatifDepartment of Chemistry, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.
Heba M MetwallyDepartment of Chemistry, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt. hebama@mans.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

1,3,4-Oxadiazoles are a vital class of heterocyclic compounds known for their diverse biological activities. In this study, a series of eight novel 1,3,4-oxadiazolyl sulfide derivatives 4a-h were synthesized and characterized using IR, NMR, and elemental analysis. The antioxidant activity of these derivatives was evaluated via DPPH and ABTS assays, revealing promising radical scavenging capabilities Compound 4 h emerged as the most potent antioxidant with SC

Indexed as

1,3,4-OxadiazoleAntioxidantDFT.Molecular dockingSAR-study

Identifiers

PMID41291811
PMCPMC12670869

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.