ArticleTrials2025
A WeChat mini-program-based intervention for orofacial myofunctional therapy in adults with obstructive sleep apnea-hypopnea syndrome: a randomized controlled trial protocol.
Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
Funding
Abstract
backgroundOrofacial myofunctional therapy (OMT) has been recommended as a safe, effective, and low-cost option for treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS). This study aims to evaluate the therapeutic effects of a WeChat mini-program-based OMT in adults with OSAHS compared to traditional home-based OMT. We hypothesize that patients trained with a WeChat mini-program-based OMT will show greater improvement in sleep quality, health-related quality of life, and exercise adherence than patients with traditional home-based rehabilitation therapy.
methodsThis study is a single-center, prospective, assessor-blinded randomized controlled trial (RCT) conducted at the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital). Patients in both groups received routine health education, with the intervention group additionally using a WeChat mini-program and the control group receiving traditional home-based OMT. The primary outcome measure is apnea-hypopnea index (AHI). Secondary outcome measures include lowest oxygen saturation (LSpO DISCUSSION: This study attempts to evaluate the efficacy and safety of telerehabilitation among OSAHS patients in China, representing our efforts in the field of telemedicine. This RCT will provide valuable evidence for remoted home-based long-term management strategies for OSAHS patients. ETHICS AND DISSEMINATION: This study has received ethics approval from the Ethics Committee of the First Affiliated Hospital of Nanjing Medical University (Ref. No. 2022-SR-600). Findings will be disseminated in a peer-reviewed journal and presented at relevant conferences.
trial registrationClinicalTrials.gov ChiCTR2300067637. Registered on January 16, 2023.
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