Evidence map›Paper›PMID 41291511›Full record

SynthesisBMC infectious diseases2025

Atopic dermatitis and its associated factors in Ethiopia: a systematic review and meta-analysis.

Tadele Lankrew Ayalew, Mulualem Gete Feleke, Kidist Ashager, Amanuel Eshetu

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tadele Lankrew AyalewDepartment of Nursing, School of Nursing, College of Health Science and Medicine, Wolaita Sodo University, P.O. Box 138, Sodo, Ethiopia. tadelelankrew@gmail.com.
Mulualem Gete FelekeDepartment of Nursing, School of Nursing, College of Health Science and Medicine, Wolaita Sodo University, P.O. Box 138, Sodo, Ethiopia.
Kidist AshagerDepartment of Nursing, School of Nursing, College of Health Science and Medicine, Wolaita Sodo University, P.O. Box 138, Sodo, Ethiopia.
Amanuel EshetuDepartment of Nursing, School of Nursing, College of Health Science and Medicine, Wachemo University, Hosanna, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtopic dermatitis is a common, chronic inflammatory skin disease that causes discomfort, emotional distress, and reduced quality of life. Although widespread globally, evidence on its prevalence and risk factors in Ethiopia is limited and fragmented, hindering effective prevention and management strategies.

objectiveThis study aims to determine the prevalence and associated factors of atopic dermatitis in Ethiopia through a systematic review and meta-analysis.

methodsWe conducted a systematic review and meta-analysis to estimate the prevalence and risk factors of atopic dermatitis in Ethiopia. Databases including PubMed, Embase, Scopus, and Web of Science, CINAHL, African Journals Online, Google Scholar, and Ethiopian repositories were searched up to August 1, 2025. Observational studies reporting prevalence or associated factors were included. Data were extracted and quality assessed by two reviewers. Pooled prevalence and odds ratios were calculated using a random-effects model, with heterogeneity, subgroup, sensitivity analyses, and publication bias assessment performed.

resultsA total of 16 studies including 22,994 participants were included in the analysis. The pooled prevalence of atopic dermatitis in Ethiopia was 26% (95% CI: 1670-35.29% I² = 99.7%, p < 0.001). Subgroup analysis showed the highest prevalence in the central Ethiopia (76.92%, 95% CI: 72.81-81.04%), followed by south Ethiopia region (67.90%( 95% CI: 63.63-72.16), and the lowest in Tigray region (9.54%, 95% CI: 6.86-12.23%). Significant determinants of atopic dermatitis among Ethiopian populations included helminth infection (AOR = 2.80, 95% CI: 1.46-4.14), family history of allergy (AOR = 3.74, 95% CI: 2.32-5.17), personal history of allergy (AOR = 3.52, 95% CI: 1.59-5.46), and exposure to environmental allergens (AOR = 3.75, 95% CI: 2.38-5.11).

conclusionAtopic dermatitis is highly prevalent in Ethiopia with notable regional variations. Helminth infection, allergic history, and environmental exposures are major risk factors, underscoring the need for targeted interventions, enhanced diagnostics, and comprehensive public health strategies.

Indexed as

Dermatitis, AtopicEthiopiaFemaleHumansPrevalenceRisk FactorsAtopic dermatitisEczemaEthiopiaPrevalenceRisk factorsSystematic review

Identifiers

PMID41291511
PMCPMC12648865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.