Observational studyBMC geriatrics2025
Examination of the healthy aging center data.
Observational study in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Linkages between functional independence, depressive symptoms, and social networks in aging populations: a systematic review.Journal of exercise rehabilitation · 2026Review
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backroundThis study aimed to characterize the health, functional, cognitive, nutritional, and psychological profiles of very old adults (≥ 80 years) enrolled in a community-based Healthy Aging Center (HAC) program.
methodsA cross-sectional observational study was conducted among community-dwelling individuals aged ≥ 80 years who completed home-based interviews between October 2023 and March 2024. Participants were assessed using the Clinical Frailty Scale (CFS), Katz Index of Activities of Daily Living (ADL), Lawton-Brody Instrumental ADL (IADL), Mini-Cog, Mini-Mental State Examination (MMSE), Geriatric Depression Scale-Short Form (GDS-SF), Patient Health Questionnaire-2 (PHQ-2), Mini Nutritional Assessment-Short Form (MNA-SF), Timed Up and Go (TUG), and Sit-to-Stand (STS) tests. Descriptive analyses, bivariate group comparisons (χ² and t-tests), and correlation analyses were performed. Missing data were reported for each scale, and sensitivity analyses were conducted to minimize bias.
resultsA total of 337 participants (mean age 85.3 ± 4.5 years; 51.9% women) were included. Based on the CFS, 27.9% (n = 94) were classified as vulnerable, 20.8% (n = 70) as mildly frail, and 18.1% (n = 61) as moderately frail. According to the Katz ADL, 61.7% were partially dependent and 37.4% fully independent; similar patterns were observed with Lawton IADL. Cognitive impairment was more prevalent in women (57.3% vs. 32.6%, p < 0.001), who also had higher rates of depression (p < 0.001), frailty (p = 0.011), and functional dependence. Men demonstrated better mobility performance on the TUG and STS (p = 0.004). Depressive symptoms correlated with both poorer health status (r = 0.421, p < 0.001) and malnutrition risk (r = - 0.364, p < 0.001). Malnutrition was associated with greater frailty (p = 0.022) and depression (p < 0.001). Dementia was more common in the oldest participants (p = 0.005), particularly those with neurological conditions (p = 0.035).
conclusionFrailty, malnutrition, cognitive impairment, and depressive symptoms were frequent among community-dwelling very old adults, particularly women. These cross-sectional findings emphasize the need for multidisciplinary and gender-sensitive strategies within HACs to support functional independence and mental well-being. Longitudinal and multivariate studies are warranted to confirm these associations.
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