ArticleNature2026
Polyclonal origins of human premalignant colorectal lesions.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Spatial Integration of Protein and Chromosomal States Reveals Early Copy-Number Changes and Genotype-Associated Immune Neighborhoods in Serous Ovarian Cancer Evolution.Cancer discovery · 2026Article
- Epigenetic Dysregulation of Tissue-resident VSELs Drives Clonal Events, Including Somatic Mutations & Eventually Cancer.Stem cell reviews and reports · 2026Article
- Colibactin-associated mutations in the human colon appear to reflect anatomy and early exposure, not oncogenesis.medRxiv : the preprint server for health sciences · 2026Article
- GCell research · 2026Article
- Article
Corrections and comments
- Update of
Authors and funding
42 authors.
Debra Van Egeren *Department of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-4017-0413
Ryan O Schenck *Department of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Aziz Khan *Department of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-6459-6224
Aaron M Horning *Department of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-3247-0798
Shanlan Mo *State Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Clemens L Weiß *Department of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Edward D EsplinDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-9205-3756
Winston R BeckerDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-7876-5060
Si WuDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Casey HansonDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-7818-6552
Nasim BarapourDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-6244-8781
Lihua JiangDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Kévin ContrepoisDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Hayan LeeDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-0571-3192
Stephanie A NevinsDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Tuhin K GuhaDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Hao ZhangState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID http://orcid.org/0000-0002-1005-2133
Zhen HeKey Laboratory of Human Microbiome and Chronic Diseases, Sun Yat-sen University, Ministry of Education, Guangzhou, China.ORCID http://orcid.org/0000-0001-8735-6672
Zhicheng MaDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Emma MonteDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Thomas V KarathanosDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Rozelle LaquindanumDepartment of Medicine, Stanford School of Medicine, Stanford, CA, USA.
Meredith A MillsDepartment of Medicine, Stanford School of Medicine, Stanford, CA, USA.
Hassan ChaibDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Roxanne ChiuDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Ruiqi JianDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-2406-5303
Joanne ChanDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Mathew EllenbergerDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Bahareh BahmaniDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-6966-6685
Basil MichaelDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Annika K WeimerDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
D Glen EsplinAnimal Reference Pathology, Salt Lake City, UT, USA.
Samuel LancasterDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Jeanne ShenDepartment of Pathology, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-1519-0308
Uri LadabaumDepartment of Medicine, Stanford School of Medicine, Stanford, CA, USA.
Teri A LongacreDepartment of Pathology, Stanford School of Medicine, Stanford, CA, USA.
Anshul KundajeDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-3084-2287
William J GreenleafDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-1409-3095
Zheng HuDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-1552-0060
James M FordDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-2513-7025
Michael P SnyderDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-0784-7987
Christina CurtisDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA. cncurtis@stanford.edu.ORCID http://orcid.org/0000-0003-0166-3802
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer is generally thought to be caused by expansion of a single mutant cell
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LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.