ArticleEye (London, England)2026
Biomechanical changes and associated factors of preserved SMILE-derived corneal stromal lenticules.
Article in Eye (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the biomechanical changes and associated factors of SMILE-derived lenticules under various preservation conditions.
methodsA total of 520 corneal stromal lenticules of 260 patients (male: female 98:162, age 28.54 ± 5.98 years, mean spherical error -4.47 ± 1.63 D) were derived during small incision lenticule extraction (SMILE) surgeries, and were stored in glycerol, silicone oil, Optisol and cryopreservation for 1 day, 1 week or 1 month. Spherical error, cylindrical error as well as other main parameters were evaluated. A nanoindenter system was used to measure the effective Young's modulus of each lenticule. Changes in effective Young's modulus were evaluated in each group among all time points.
resultsThere was no statistical significance in effective Young's moduli of lenticules in the glycerol group among all preservation times, while the lowest effective Young's modulus appeared when preserved for 1 month, 1 week, and 1 day in the silicone oil, Optisol, and cryopreservation group. Among all factors observed, the spherical error of SMILE-derived lenticules was a positive influencing factor on their biomechanics (P = 0.04*).
conclusionsIt is feasible to maintain biomechanical stability of SMILE-derived lenticules in glycerol in the short term. Thickness is a positive influencing factor on the biomechanics of SMILE-derived lenticules.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.